SCHEMBL838877

SCHEMBL838877

O=C(O)C12C3C4C1C1C2C3C41C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 1/20 0.55
GRM1 Q13255 1/20 0.55
GRM2 Q14416 1/20 0.55
GRM4 Q14833 1/20 0.55
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
FFAR3 O14843 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10875068 0.96 GRM5 (0.52) GRM5GRM1GRM2GRM4
SCHEMBL20130279 0.87 GRM5 (0.46) GRM5GRM1GRM2GRM4FFAR3
SCHEMBL15055615 0.84 GRM5 (0.50) GRM5GRM1GRM2GRM4
SCHEMBL16887658 0.84 GRM5 (0.44) GRM5GRM1GRM2GRM4FFAR3
SCHEMBL4732666 0.82 GRM5 (0.42) GRM5GRM1GRM2GRM4
Hydrochloric Acid SCHEMBL26963918 0.82 GRM4 (0.48) GRM5GRM1GRM2GRM4
Hydrochloric Acid SCHEMBL10875811 0.79 GRM5 (0.41) GRM5GRM1GRM2GRM4
SCHEMBL5313701 0.78 GRM5 (0.40) GRM5GRM1GRM2GRM4
SCHEMBL16886352 0.78 GRM5 (0.45) GRM5GRM1GRM2GRM4
SCHEMBL10875010 0.78 GRM5 (0.45) GRM5GRM1GRM2GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116987102-A Preparation of complex with thermal activation delayed fluorescence property and application of scintillator 南开大学 2023-11-03 CN claimed
EP-3704094-B1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2026-03-11 EP disclosed
CN-121574071-A Binary hydroxamic acid compound, rare earth metal organic framework material, and preparation methods and applications thereof 浙江大学衢州研究院 2026-02-27 CN disclosed
WO-2025137053-A1 WEE1 DEGRADING COMPOUNDS AND USES THEREOF BRISTOL-MYERS SQUIBB COMPANY (US) 2025-06-26 WO disclosed
US-20250197374-A1 WEE1 DEGRADING COMPOUNDS AND USES THEREOF BRISTOL-MYERS SQUIBB COMPANY 2025-06-19 US disclosed
US-20250122188-A1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2025-04-17 US disclosed
WO-2025079720-A1 HALOGENATED CUBANE COMPOUND AND PRODUCTION METHOD FOR SAME AGC株式会社 2025-04-17 WO disclosed
US-20240166652-A1 MODULATORS OF THE INTEGRATED STRESS PATHWAY ABBVIE INC. 2024-05-23 US disclosed
US-20240140939-A1 COMPOSITIONS AND METHODS FOR REDUCING PHOTO DAMAGE DURING SEQUENCING ILLUMINA, INC. 2024-05-02 US disclosed
EP-4356971-A2 MODULATORS OF THE INTEGRATED STRESS PATHWAY Calico Life Sciences LLC (US) 2024-04-24 EP disclosed
WO-2001066147-A2 ANTIMICROBIAL COMPOUNDS AND FORMULATIONS ALPHARMA AS (NO) 2001-09-13 WO disclosed
EP-1109831-A2 CYCTOTOXIC PEPTIDES MODIFIED BY BULKY OR LIPOPHILIC MOIETIES ALPHARMA AS (NO) 2001-06-27 EP disclosed
EP-1109827-A2 BIOACTIVE PEPTIDES ALPHARMA AS (NO) 2001-06-27 EP disclosed
WO-2000012541-A2 CYTOTOXIC PEPTIDES MODIFIED BY BULKY OR LIPOPHILIC MOIETIES ALPHARMA AS (NO) 2000-03-09 WO disclosed
WO-2000012542-A2 CYTOTOXIC LACTOFERRIN DERIVATIVES MODIFIED BY BULKY OR LIPOPHILIC MOIETIES ALPHARMA AS (NO) 2000-03-09 WO disclosed
EP-0324609-B1 OXIDIZING SALTS OF CUBYL AMINES THIOKOL CORPORATION (US) 1992-03-25 EP disclosed
US-4878968-A LIQUID PROPELLANTS MORTON THIOKOL, INC. (US) 1989-11-07 US disclosed
EP-0324609-A1 Oxidizing salts of cubyl amines THIOKOL CORPORATION (US) 1989-07-19 EP disclosed
EP-0181926-A1 SUBSTITUTED CUBANES UNIVERSITY PATENTS, INC. (US) 1986-05-28 EP disclosed
WO-1985005357-A1 SUBSTITUTED CUBANES UNIVERSITY PATENTS, INC. (US) 1985-12-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240140939-A1 COMPOSITIONS AND METHODS FOR REDUCING PHOTO DAMAGE DURING SEQUENCING OGG1, POLL, POLRMT GRM5 3969/4885GRM1 4585/4885GRM2 4288/4885
US-20250122188-A1 MODULATORS OF THE INTEGRATED STRESS PATHWAY ATF4, ATF1, DDIT3 GRM5 1226/4885GRM1 1417/4885GRM2 875/4885
US-20240166652-A1 MODULATORS OF THE INTEGRATED STRESS PATHWAY ATF4, ATF1, DDIT3 GRM5 1226/4885GRM1 1417/4885GRM2 875/4885
US-20250197374-A1 WEE1 DEGRADING COMPOUNDS AND USES THEREOF WEE1, WEE2, PPME1 GRM5 4137/4885GRM1 3904/4885GRM2 3779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.