Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | RECQL | P46063 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 6/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GRK5 | P34947 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526678 | 0.88 | MEN1 (0.55) | MEN1KMT2AMAPTRECQLPOLB | |
| SCHEMBL11383528 | 0.88 | MEN1 (0.68) | MEN1KMT2AMAPTRECQLPOLB | |
| SCHEMBL10061485 | 0.85 | MAPT (0.55) | MEN1KMT2AMAPTRECQLPOLB | |
| SCHEMBL10867193 | 0.85 | KMT2A (0.74) | MEN1KMT2AMAPTRECQLPOLB | |
| SCHEMBL9345251 | 0.84 | KMT2A (0.64) | MEN1KMT2AMAPTRECQLPOLB | |
| SCHEMBL11049234 | 0.83 | MEN1 (0.70) | MEN1KMT2AMAPTRECQLPOLB | |
| SCHEMBL11047439 | 0.82 | MEN1 (0.72) | MEN1KMT2AMAPTRECQLPOLB | |
| SCHEMBL10873637 | 0.81 | KMT2A (0.56) | MEN1KMT2AMAPTRECQLPOLB | |
| SCHEMBL9344030 | 0.81 | MEN1 (0.57) | MEN1KMT2AMAPTRECQLPOLB | |
| SCHEMBL14020046 | 0.81 | KMT2A (0.51) | MEN1KMT2AMAPTRECQLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067845-B1 | A METHOD FOR PREPARING 2-PYRAZOLIN-5-ONES FROM 1,2,4-OXADIAZOLES | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1986-06-11 | — | — | EP | disclosed |
| EP-0067845-A4 | A METHOD FOR PREPARING 2-PYRAZOLIN-5-ONES FROM 1,2,4-OXADIAZOLES. | EASTMAN KODAK CO (US) | 1983-04-25 | — | — | EP | disclosed |
| EP-0067845-A1 | A METHOD FOR PREPARING 2-PYRAZOLIN-5-ONES FROM 1,2,4-OXADIAZOLES. | EASTMAN KODAK CO (US) | 1982-12-29 | — | — | EP | disclosed |
| US-4345085-A | BASIC CATALYSTS, REARRANGEMENTS | EASTMAN KODAK COMPANY (US) | 1982-08-17 | — | — | US | disclosed |
| WO-1982002198-A1 | A METHOD FOR PREPARING 2-PYRAZOLIN-5-ONES FROM 1,2,4-OXADIAZOLES | EASTMAN KODAK CO (US) | 1982-07-08 | — | — | WO | disclosed |