Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GRK5 | P34947 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10875014 | 0.88 | MEN1 (0.68) | MEN1KMT2AMAPTPOLBRECQL | |
| SCHEMBL124737 | 0.76 | MEN1 (0.72) | MEN1KMT2AMAPTPOLBRECQL | |
| SCHEMBL10867193 | 0.74 | KMT2A (0.74) | MEN1KMT2AMAPTPOLBRECQL | |
| SCHEMBL10061485 | 0.74 | MAPT (0.55) | MEN1KMT2AMAPTPOLBRECQL | |
| SCHEMBL11049234 | 0.72 | MEN1 (0.70) | MEN1KMT2AMAPTPOLBRECQL | |
| SCHEMBL9727104 | 0.72 | P2RX1 (0.50) | MEN1KMT2AMAPTPOLBP2RX1 | |
| SCHEMBL11047439 | 0.72 | MEN1 (0.72) | MEN1KMT2AMAPTPOLBRECQL | |
| SCHEMBL3190354 | 0.71 | MAPT (0.53) | MEN1KMT2AMAPTPOLBRECQL | |
| SCHEMBL9525446 | 0.71 | TDP1 (0.43) | MEN1KMT2AMAPTL3MBTL1GAA | |
| SCHEMBL10873637 | 0.70 | KMT2A (0.56) | MEN1KMT2AMAPTPOLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274642-B1 | HERBICIDAL AND FUNGICIDAL AGENTS BASED ON SUBSTITUTED PYRAZOLIN-5-ONE DERIVATIVES | BAYER AG (DE) | 1993-08-11 | — | — | EP | disclosed |
| US-5162528-A | Pre- and post-emergence; phytaphthora in tomato plants; rice and wheat | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-10 | — | — | US | disclosed |
| US-5028717-A | Herbicidal and fungicidal agents based on substituted pyrazolin-5-one derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |
| US-4909827-A | Containing a C6-10 aryl group substituted in position 1 | BAYER AKTIENGESELLSCHAFT (DE) | 1990-03-20 | — | — | US | disclosed |