Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.55 |
| ▸ | HTT | P42858 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11020702 | 0.79 | SMN1; SMN2 (0.54) | POLBSMN1; SMN2HTTRAB9AHIF1A | |
| SCHEMBL10875783 | 0.75 | SMN1; SMN2 (0.57) | POLBSMN1; SMN2HTTRAB9AHIF1A | |
| SCHEMBL9387866 | 0.75 | CLK4 (0.42) | POLBSMN1; SMN2HTTHIF1ATSHR | |
| SCHEMBL21636908 | 0.75 | CYP1A2 (0.58) | SMN1; SMN2HTTRAB9AHIF1ATSHR | |
| SCHEMBL10877514 | 0.73 | CYP1A2 (0.61) | SMN1; SMN2RAB9ATSHRMEN1KMT2A | |
| SCHEMBL17009430 | 0.73 | POLB (1.00) | POLBSMN1; SMN2HTTRAB9AHIF1A | |
| SCHEMBL14779321 | 0.72 | SMN1; SMN2 (0.56) | POLBSMN1; SMN2HTTRAB9AHIF1A | |
| SCHEMBL20119913 | 0.71 | POLB (0.66) | POLBSMN1; SMN2HTTRAB9AHIF1A | |
| Kinetin SCHEMBL15705 | 0.71 | SMN1; SMN2 (0.66) | POLBSMN1; SMN2HTTRAB9AHIF1A | |
| Kinetin SCHEMBL29829493 | 0.71 | SMN1; SMN2 (0.66) | POLBSMN1; SMN2HTTRAB9AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206415-A2 | (4-Piperidinylmethyl and -hetero)purines | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-12-30 | — | — | EP | disclosed |