Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 10/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | TSHR | P16473 | 6/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | EGFR | P00533 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | GALR3 | O60755 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10874378 | 0.84 | HTT (0.52) | CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL10875900 | 0.80 | EGFR (0.54) | CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL3712006 | 0.77 | RPS6KB1 (0.63) | CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL11716564 | 0.77 | EGFR (0.51) | ALDH1A1TSHRMAPK1LMNAEGFR | |
| SCHEMBL6285864 | 0.76 | BACE1 (0.65) | ALDH1A1TSHRMAPK1LMNAEGFR | |
| SCHEMBL31631318 | 0.76 | BACE1 (0.65) | ALDH1A1TSHRMAPK1LMNAEGFR | |
| SCHEMBL10877514 | 0.75 | CYP1A2 (0.61) | CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL10875724 | 0.75 | POLB (0.58) | CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL12069119 | 0.74 | APP (0.55) | LMNAEGFR | |
| SCHEMBL16489595 | 0.74 | NOS2 (0.49) | CYP1A2CYP3A4CYP2D6CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020016605-A1 | POLYNUCLEOTIDE SYNTHESIS METHOD, KIT AND SYSTEM | OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) | 2020-01-23 | — | — | WO | disclosed |