Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11204299 | 0.93 | TDP1 (0.59) | TDP1SMN1; SMN2MMP8L3MBTL1MAPK1 | |
| SCHEMBL11203243 | 0.88 | TDP1 (0.57) | TDP1SMN1; SMN2MMP8L3MBTL1MAPK1 | |
| SCHEMBL6714506 | 0.88 | TDP1 (0.65) | TDP1SMN1; SMN2MMP8L3MBTL1MAPK1 | |
| SCHEMBL10878509 | 0.87 | MMP8 (0.56) | TDP1SMN1; SMN2MMP8L3MBTL1MAPK1 | |
| SCHEMBL11202434 | 0.87 | TDP1 (0.56) | TDP1SMN1; SMN2MMP8L3MBTL1MAPK1 | |
| SCHEMBL11201035 | 0.87 | TDP1 (0.56) | TDP1SMN1; SMN2MMP8L3MBTL1MAPK1 | |
| SCHEMBL11202095 | 0.87 | TDP1 (0.56) | TDP1SMN1; SMN2MMP8L3MBTL1MAPK1 | |
| SCHEMBL10874645 | 0.87 | TDP1 (0.56) | TDP1SMN1; SMN2MMP8L3MBTL1MAPK1 | |
| SCHEMBL2422561 | 0.84 | TDP1 (0.56) | TDP1SMN1; SMN2MMP8L3MBTL1MAPK1 | |
| SCHEMBL8171961 | 0.84 | TDP1 (0.63) | TDP1SMN1; SMN2MMP8L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071175-B1 | PHENYLALKYLOXIRANE-CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1986-03-12 | — | — | EP | disclosed |
| EP-0071175-A2 | Phenylalkyloxirane-carboxylic acids, process for their preparation, their use and medicines containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1983-02-09 | — | — | EP | disclosed |
| WO-1983000334-A1 | PHENYLALKYLOXIRANE CARBOXYLIC ACIDS, PREPARATION AND THERAPEUTICAL USE | KOHL, BERNHARD | 1983-02-03 | — | — | WO | disclosed |