Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 5/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.39 |
| ▸ | DCK | P27707 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774919 | 0.86 | DPP4 (0.44) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL10876624 | 0.86 | DPP4 (0.43) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL10876232 | 0.85 | DPP4 (0.59) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9533039 | 0.83 | DPP4 (0.40) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL10874661 | 0.83 | DPP4 (0.49) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL10377709 | 0.83 | DPP4 (0.51) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9837373 | 0.82 | DPP4 (0.49) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL10377270 | 0.82 | DPP4 (0.50) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL10377338 | 0.82 | DPP4 (0.50) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9279265 | 0.82 | DPP4 (0.42) | DPP4CHRM2DRD1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203488-A2 | 7-Azolyl-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinoline carboxylic acids and 1,8-naphthyridine carboxylic acids, process for their preparation and bactericidal agents containing them | BAYER AG (DE) | 1986-12-03 | — | — | EP | disclosed |