Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14582037 | 0.88 | APP (0.49) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11983560 | 0.87 | KMT2A (0.51) | APPRECQLHDAC3HDAC4HDAC1 | |
| SCHEMBL13383124 | 0.84 | APP (0.46) | APPHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7132118 | 0.83 | RECQL (0.51) | RECQLALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL1915834 | 0.82 | RECQL (0.69) | RECQLKMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL1915837 | 0.82 | RECQL (0.69) | RECQLKMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL1915838 | 0.82 | RECQL (0.69) | RECQLKMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL7617840 | 0.81 | GSK3B (0.50) | RECQLHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL2171291 | 0.81 | MEN1 (0.50) | RECQLALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL27725356 | 0.81 | RECQL (0.58) | RECQLHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153615-B2 | Synthesis of glycerolipid carbamates and dicarbamates and their use as an antitumor compounds | THE UNIVERSITY OF MANITOBA (CA) | 2012-04-10 | — | — | US | disclosed |
| US-20090042811-A1 | Synthesis of Glycerolipid Carbamates and Dicarbamates and Their Use as an Antitumor Compounds | THE UNIVERSITY OF MANITOBA (CA) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042811-A1 | Synthesis of Glycerolipid Carbamates and Dicarbamates and Their Use as an Antitumor Compounds | PHOSPHO1, SGMS1, UGCG | APP 4684/4885RECQL 2626/4885HDAC3 421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.