Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 15/20 | 0.41 |
| ▸ | NMBR | P28336 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10871413 | 1.00 | SIRT2 (0.41) | SIRT2NMBRALDH1A1CES2ACHE | |
| SCHEMBL10871417 | 0.80 | SIRT2 (0.40) | SIRT2NMBRCES2CES1 | |
| SCHEMBL3573464 | 0.80 | SIRT2 (0.49) | SIRT2NMBRALDH1A1 | |
| Alcohol SCHEMBL6432975 | 0.79 | SIRT2 (0.47) | SIRT2NMBRALDH1A1 | |
| SCHEMBL7713289 | 0.76 | SIRT2 (0.46) | SIRT2NMBRALDH1A1 | |
| SCHEMBL6777569 | 0.76 | SIRT2 (0.48) | SIRT2NMBRALDH1A1 | |
| SCHEMBL23278623 | 0.75 | SIRT2 (0.46) | SIRT2NMBR | |
| SCHEMBL9060018 | 0.74 | SIRT2 (0.41) | SIRT2ALDH1A1 | |
| SCHEMBL2034215 | 0.74 | SIRT2 (0.46) | SIRT2SMN1; SMN2 | |
| SCHEMBL14901171 | 0.73 | SIRT2 (0.46) | SIRT2NMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61130273-A | — | — | None | — | — | JP | disclosed |
| JP-S61130273-A | ALPHA-OXYIMINOBUTYRIC ACID DERIVATIVE, AND PREPARATION THEREOF | DAI ICHI SEIYAKU CO LTD | 1986-06-18 | — | — | JP | disclosed |