Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 12/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070031 | 0.88 | ALDH1A1 (0.49) | SIRT2ALDH1A1MAPTLMNAGABRA2 | |
| SCHEMBL5266089 | 0.87 | SIRT2 (0.41) | SIRT2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9789313 | 0.84 | SIRT2 (0.42) | SIRT2ALDH1A1LMNAGABRA2GABRB2 | |
| SCHEMBL1040797 | 0.82 | RAB9A (0.39) | SIRT2ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL1040796 | 0.82 | RAB9A (0.39) | SIRT2ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL1414901 | 0.81 | SIRT2 (0.40) | SIRT2MAPTL3MBTL1 | |
| SCHEMBL1040045 | 0.79 | CYP11B1 (0.41) | SIRT2ALDH1A1MAPTKMT2A | |
| SCHEMBL10457151 | 0.78 | HPGD (0.39) | SIRT2L3MBTL1GABRA2GABRB2 | |
| SCHEMBL5682164 | 0.78 | CYP11B1 (0.43) | SIRT2KMT2A | |
| SCHEMBL670904 | 0.78 | CYP11B1 (0.43) | SIRT2ALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996017840-A1 | HETEROCYCLYL SUBSTITUTED HYDROXYACETAMIDE DERIVATIVES AS FONGICIDES | AGREVO UK LIMITED (GB) | 1996-06-13 | — | — | WO | disclosed |