Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 4/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10876432 | 0.88 | TDP1 (0.53) | LTA4HTRPM8ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL465562 | 0.86 | LTA4H (0.59) | LTA4HALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL10874997 | 0.85 | MAPT (0.44) | LTA4HALDH1A1NPC1LMNAALOX15 | |
| SCHEMBL10877393 | 0.83 | LTA4H (0.56) | LTA4HTRPM8SMN1; SMN2NPC1LMNA | |
| SCHEMBL10878976 | 0.80 | LTA4H (0.43) | LTA4HALDH1A1SMN1; SMN2FFAR4 | |
| SCHEMBL10874866 | 0.80 | FFAR4 (0.50) | LTA4HALDH1A1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL10878574 | 0.80 | KDM4E (0.56) | LTA4HALDH1A1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL10878193 | 0.79 | PPARA (0.45) | LTA4HALDH1A1SMN1; SMN2NPC1FFAR4 | |
| SCHEMBL10879948 | 0.77 | TDP1 (0.49) | LTA4HTRPM8ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL10878256 | 0.77 | LPAR1 (0.48) | LTA4HALDH1A1SMN1; SMN2NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4625048-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1986-11-25 | — | — | US | disclosed |