Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 11/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2933964 | 1.00 | DNM1 (0.60) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL6350234 | 1.00 | DNM1 (0.60) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL1537141 | 1.00 | DNM1 (0.60) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL5860626 | 1.00 | DNM1 (0.60) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL5859492 | 1.00 | DNM1 (0.60) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL1685498 | 1.00 | DNM1 (0.60) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL4804737 | 1.00 | DNM1 (0.60) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL6350372 | 1.00 | DNM1 (0.60) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL8162957 | 1.00 | DNM1 (0.60) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL1784336 | 1.00 | DNM1 (0.60) | DNM1TSHRMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114387-B1 | BIS-GUANIDINE COMPOUND SALTS, THEIR PREPARATION AND MICROBICIDAL USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-02-05 | — | — | EP | disclosed |
| EP-0114387-A1 | Bis-guanidine compound salts, their preparation and microbicidal use | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-08-01 | — | — | EP | disclosed |