Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 4/20 | 0.72 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10878998 | 0.93 | EBP (0.63) | EBPSIGMAR1KMT2AMEN1NPSR1 | |
| SCHEMBL10878610 | 0.87 | EBP (0.57) | EBPSIGMAR1KMT2AMEN1NPSR1 | |
| SCHEMBL10356744 | 0.87 | CYP2D6 (0.58) | EBPSIGMAR1KMT2AMEN1NPSR1 | |
| SCHEMBL10746230 | 0.87 | EBP (0.56) | EBPSIGMAR1HRH3KDM4EMAPT | |
| SCHEMBL10880656 | 0.86 | EBP (0.55) | EBPSIGMAR1KMT2AMEN1NPSR1 | |
| SCHEMBL10358944 | 0.85 | EBP (0.62) | EBPSIGMAR1KMT2AMEN1NPSR1 | |
| SCHEMBL4310502 | 0.85 | EBP (0.81) | EBPSIGMAR1KMT2AMEN1NPSR1 | |
| Triparanol SCHEMBL133384 | 0.84 | EBP (1.00) | EBPSIGMAR1KMT2AMEN1NPSR1 | |
| SCHEMBL10794219 | 0.84 | EBP (0.53) | EBPSIGMAR1KMT2AMEN1NPSR1 | |
| SCHEMBL10794296 | 0.84 | EBP (0.53) | EBPSIGMAR1KMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4605672-A | ANTIDEPRESSANTS; TREATMENT OF ETHANOLIC INTOXICATION; LOW TOXICITY AND FEW SIDE EFFECTS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1986-08-12 | — | — | US | claimed |
| EP-0115080-B1 | (OMEGA-(DIETHYLAMINO)-ALKOXY)-ALPHA-(ETHYL)-BENZHYDROL DERIVATIVES, THEIR ACID ADDITION SALTS AND QUATERNARY SALTS, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-04-16 | — | — | EP | claimed |
| US-4605672-A | ANTIDEPRESSANTS; TREATMENT OF ETHANOLIC INTOXICATION; LOW TOXICITY AND FEW SIDE EFFECTS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1986-08-12 | — | — | US | disclosed |