Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11621538 | 0.87 | MAPT (0.81) | MAPTALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL10099553 | 0.84 | MAPT (0.64) | MAPTALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL9827893 | 0.83 | MAPT (0.70) | MAPTALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL3704980 | 0.81 | MAPT (0.68) | MAPTALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL4782773 | 0.81 | MAPT (0.67) | MAPTALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL5940592 | 0.80 | RAB9A (0.74) | MAPTALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL14066860 | 0.80 | MAPT (0.62) | MAPTALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL23842313 | 0.80 | HDAC1 (0.78) | MAPTALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL2558734 | 0.80 | MAPT (0.69) | MAPTALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL8612164 | 0.80 | HDAC1 (0.78) | MAPTALDH1A1KDM4EUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199042-A1 | Procainamide assay, tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-10-29 | — | — | EP | disclosed |