Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10881227 | 0.99 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNASTAT3PPARGPPARA | |
| SCHEMBL11035166 | 0.82 | PLA2G4B (0.57) | SMN1; SMN2LMNASTAT3PPARGPPARA | |
| SCHEMBL2832501 | 0.81 | SMN1; SMN2 (0.67) | SMN1; SMN2LMNASTAT3NR1H4MAPT | |
| SCHEMBL10879903 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNASTAT3PPARGPPARA | |
| SCHEMBL10879167 | 0.81 | ADRB2 (0.63) | SMN1; SMN2LMNASTAT3NR1H4MAPT | |
| SCHEMBL10879545 | 0.81 | ADRB2 (0.63) | SMN1; SMN2LMNASTAT3NR1H4MAPT | |
| Hydrochloric Acid SCHEMBL10878728 | 0.80 | ADRB2 (0.61) | SMN1; SMN2LMNASTAT3PPARGNR1H4 | |
| SCHEMBL22192246 | 0.80 | SMN1; SMN2 (0.81) | SMN1; SMN2LMNASTAT3NR1H4MAPT | |
| SCHEMBL10880581 | 0.80 | ADRB2 (0.64) | SMN1; SMN2LMNASTAT3NR1H4MAPT | |
| SCHEMBL8757069 | 0.79 | SMN1; SMN2 (0.67) | SMN1; SMN2LMNASTAT3NR1H4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0100051-B1 | NEW DERIVATIVES OF 1-ALKYLAMINE-(4(P-ALKYLOXY-BENZAMIDE)PHENOXY)-2-PROPANOL, HAVING BETA-SYMPATHOLYTIC ACTIVITY, THEIR SALTS, AND PRODUCTION PROCESSES THEREOF | A. Menarini S.a.S. (IT) | 1986-04-09 | — | — | EP | claimed |