SCHEMBL10879486

SCHEMBL10879486

Cc1cccc(Cc2cccc(CBr)c2)c1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.48
IDO1 P14902 2/20 0.47
DAO P14920 2/20 0.45
ACHE P22303 1/20 0.44
LTA4H P09960 1/20 0.43
MAOB P27338 2/20 0.42
ALDH1A1 P00352 2/20 0.41
MAPK1 P28482 1/20 0.41
SLC5A2 P31639 1/20 0.41
TRPA1 O75762 1/20 0.41
TSHR P16473 1/20 0.41
HRH3 Q9Y5N1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL177507 0.91
SCHEMBL30589449 0.91
SCHEMBL7274625 0.89 TAAR1 (0.54) TAAR1IDO1ACHEMAOBALDH1A1
SCHEMBL11031399 0.89 TAAR1 (0.54) TAAR1IDO1ACHEMAOBALDH1A1
SCHEMBL15389994 0.87 TRPA1 (0.52) TAAR1ALDH1A1TRPA1TSHR
SCHEMBL30000562 0.87 TAAR1 (0.60) TAAR1IDO1DAOACHELTA4H
SCHEMBL1263547 0.87 TAAR1 (0.60) TAAR1IDO1DAOACHELTA4H
SCHEMBL29459538 0.87 TAAR1 (0.60) TAAR1IDO1DAOACHELTA4H
SCHEMBL10879452 0.86 SLC5A2 (0.42) IDO1DAOLTA4HMAOBALDH1A1
Trimethylammonium SCHEMBL6257520 0.85 TAAR1 (0.50) TAAR1IDO1ACHEMAOBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0094085-B1 ETHER COMPOUNDS, THEIR PRODUCTION AND AN INSECTICIDAL AND/OR ACARICIDAL COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-01-02 EP disclosed
US-4562213-A Certain phenoxy-benzyloxy ether derivatives and an insecticidal and/or acaricidal composition containing the same and methods of use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-12-31 US disclosed
EP-0094085-A1 Ether compounds, their production and an insecticidal and/or acaricidal composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-11-16 EP disclosed