Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438393 | 0.98 | SIGMAR1 (0.40) | CSNK1EALDH1A1KCNH2NPC1JAK2 | |
| SCHEMBL4342404 | 0.93 | POLB (0.37) | ALDH1A1KCNH2NPC1JAK2RAB9A | |
| SCHEMBL8438389 | 0.86 | NPC1 (0.39) | CSNK1EALDH1A1KCNH2NPC1JAK2 | |
| SCHEMBL7163078 | 0.86 | NPC1 (0.39) | CSNK1EALDH1A1KCNH2NPC1JAK2 | |
| SCHEMBL28298055 | 0.85 | TP53 (0.39) | ALDH1A1KCNH2SIGMAR1TP53MAPT | |
| SCHEMBL11290517 | 0.85 | CSNK1E (0.43) | CSNK1EALDH1A1KCNH2SIGMAR1MEN1 | |
| SCHEMBL5223757 | 0.84 | CSNK1E (0.42) | CSNK1EALDH1A1KCNH2NPC1JAK2 | |
| SCHEMBL5226408 | 0.84 | CSNK1E (0.42) | CSNK1EALDH1A1KCNH2NPC1JAK2 | |
| SCHEMBL13227403 | 0.83 | ESR1 (0.43) | ALDH1A1MEN1KMT2ATP53MAPT | |
| SCHEMBL2493913 | 0.82 | CSNK1E (0.41) | CSNK1EALDH1A1KCNH2NPC1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170222150-A1 | PHOTOELECTRIC CONVERSION ELEMENT | RICOH COMPANY, LTD. (JP) | 2017-08-03 | — | — | US | disclosed |
| EP-0178874-A1 | Alkylsulfonamidophenylalkylamines | ELI LILLY AND COMPANY (US) | 1986-04-23 | — | — | EP | disclosed |