Phenol

Phenol

SCHEMBL10879720

CCCCCCCCCCCCCCCS(=O)(=O)O.Oc1ccccc1

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.47
ESR2 Q92731 3/20 0.47
ALDH1A1 P00352 2/20 0.46
LMNA P02545 2/20 0.46
MEN1 O00255 1/20 0.46
MAPT P10636 1/20 0.46
MAPK1 P28482 1/20 0.46
KMT2A Q03164 1/20 0.46
NAAA Q02083 1/20 0.44
S1PR2 O95136 1/20 0.43
S1PR1 P21453 1/20 0.43
S1PR3 Q99500 1/20 0.43
ADRA2A P08913 2/20 0.43
ADORA3 P0DMS8 2/20 0.43
TACR2 P21452 2/20 0.43
SLC6A2 P23975 2/20 0.43
SLC6A4 P31645 2/20 0.43
SLC6A3 Q01959 2/20 0.43
KDM4E B2RXH2 1/20 0.43
SHBG P04278 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL27982105 0.98 ESR1 (0.45) ESR1ESR2ALDH1A1LMNAMEN1
Orthocresol SCHEMBL9871581 0.89 EPHX2 (0.41) ESR1ESR2ALDH1A1LMNAMEN1
Biphenyl SCHEMBL27876466 0.87 PTPN1 (0.48) NAAAS1PR2S1PR1S1PR3EPHX2
Benzene SCHEMBL27649746 0.87 EPHX2 (0.51) ALDH1A1S1PR2S1PR1S1PR3EPHX2
Benzene SCHEMBL11150225 0.87 EPHX2 (0.51) ALDH1A1S1PR2S1PR1S1PR3EPHX2
Benzene SCHEMBL27649739 0.87 EPHX2 (0.51) ALDH1A1S1PR2S1PR1S1PR3EPHX2
Benzene SCHEMBL28758814 0.87 EPHX2 (0.51) ALDH1A1S1PR2S1PR1S1PR3EPHX2
Benzene SCHEMBL112147 0.87 EPHX2 (0.51) ALDH1A1S1PR2S1PR1S1PR3EPHX2
Biphenyl SCHEMBL6253922 0.86 PTPN1 (0.47) NAAAS1PR2S1PR1S1PR3EPHX2
Phenol SCHEMBL17102999 0.85 CA12 (0.46) ESR1ESR2ALDH1A1LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0059679-B1 PRESSURE SENSITIVE RECORDING MATERIAL Spezial-Papiermaschinenfabrik August Alfred Krupp GmbH & Co (DE) 1986-01-15 EP claimed
US-4417752-A ESTERS OF HIGHER FATTY ACIDS SPEZIAL-PAPIERMASCHINENFABRIK AUGUST ALFRED KRUPP GMBH & CO. HILDEN BEI DUSSELDORF, (DE) 1983-11-29 US claimed
US-4417752-A ESTERS OF HIGHER FATTY ACIDS SPEZIAL-PAPIERMASCHINENFABRIK AUGUST ALFRED KRUPP GMBH & CO. HILDEN BEI DUSSELDORF, (DE) 1983-11-29 US disclosed