SCHEMBL10880428

SCHEMBL10880428

c1cc2ccc3ccc4ccc5ccc6c7c(c1CC6)c2c3c4c57

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.39
TSHR P16473 2/20 0.39
ALDH1A1 P00352 7/20 0.37
HPGD P15428 6/20 0.37
LMNA P02545 3/20 0.37
GAA P10253 3/20 0.37
MAPT P10636 2/20 0.37
KDM4E B2RXH2 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
HSD17B10 Q99714 3/20 0.37
CYP1A2 P05177 2/20 0.37
CYP1A1 P04798 1/20 0.37
CYP1B1 Q16678 1/20 0.37
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
ALOX15 P16050 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4851374 0.75 ALDH1A1 (0.48) CYP3A4TSHRALDH1A1HPGDLMNA
SCHEMBL154911 0.75 TSHR (0.70) CYP3A4TSHRALDH1A1HPGDLMNA
SCHEMBL29706425 0.75 TSHR (0.70) CYP3A4TSHRALDH1A1HPGDLMNA
Pyrene SCHEMBL27829598 0.73 ALDH1A1 (0.61) CYP3A4TSHRALDH1A1HPGDLMNA
SCHEMBL29363009 0.73 ALDH1A1 (0.58) CYP3A4TSHRALDH1A1HPGDGAA
SCHEMBL29563511 0.73 ALDH1A1 (0.58) CYP3A4TSHRALDH1A1HPGDGAA
SCHEMBL3082401 0.73 ALDH1A1 (0.58) CYP3A4TSHRALDH1A1HPGDGAA
SCHEMBL26856 0.73 ALDH1A1 (0.58) CYP3A4TSHRALDH1A1HPGDGAA
SCHEMBL28417350 0.73 ALDH1A1 (0.58) CYP3A4TSHRALDH1A1HPGDGAA
SCHEMBL31184703 0.73 ALDH1A1 (0.58) CYP3A4TSHRALDH1A1HPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017131406-A1 ORGANIC COMPOUND, THREE-DIMENSIONAL ORGANIC FRAMEWORK FORMED BY USING ORGANIC COMPOUND, SEPARATION SIEVE AND OPTICAL LAYER, WHICH COMPRISE ORGANIC FRAMEWORK, AND OPTICAL DEVICE COMPRISING OPTICAL LAYER AS OPTICAL AMPLIFICATION LAYER 한양대학교 산학협력단 2017-08-03 WO disclosed
EP-0063052-B1 STARTING PITCHES FOR CARBON FIBERS NIPPON OIL CO. LTD. (JP) 1986-09-03 EP disclosed
EP-0063053-B1 STARTING PITCHES FOR CARBON FIBERS NIPPON OIL CO. LTD. (JP) 1986-03-12 EP disclosed
US-4521294-A Starting pitches for carbon fibers NIPPON OIL CO., LTD. (JP) 1985-06-04 US disclosed
US-4397830-A HEAT TREATMENT OF HEAVY OIL AND HYDROGENATED HEAVY OIL NIPPON OIL CO., LTD. (JP) 1983-08-09 US disclosed
EP-0063052-A2 Starting pitches for carbon fibers NIPPON OIL CO. LTD. (JP) 1982-10-20 EP disclosed
EP-0063053-A2 Starting pitches for carbon fibers NIPPON OIL CO. LTD. (JP) 1982-10-20 EP disclosed