Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | PCNA | P12004 | 7/20 | 0.48 |
| ▸ | THRB | P10828 | 5/20 | 0.42 |
| ▸ | THRA | P10827 | 3/20 | 0.42 |
| ▸ | LIG1 | P18858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11200753 | 0.99 | SCN9A (0.47) | SCN9APCNATHRBTHRALIG1 | |
| Alcohol SCHEMBL5573250 | 0.85 | PCNA (0.60) | PCNATHRBTHRALIG1MEN1 | |
| SCHEMBL10883956 | 0.84 | PCNA (0.46) | SCN9APCNATHRBTHRALIG1 | |
| SCHEMBL30693721 | 0.84 | PCNA (0.66) | PCNATHRBTHRALIG1MEN1 | |
| SCHEMBL188397 | 0.84 | PCNA (0.66) | PCNATHRBTHRALIG1MEN1 | |
| Carbamic Acid SCHEMBL7215408 | 0.82 | PCNA (0.63) | PCNATHRBTHRALIG1MEN1 | |
| SCHEMBL10680951 | 0.81 | SLC7A5 (0.53) | SCN9APCNAPPARGLTA4H | |
| SCHEMBL15962606 | 0.80 | CA12 (0.41) | SCN9APCNAKMT2ALMNATSHR | |
| Sulfuric Acid SCHEMBL8910589 | 0.80 | PCNA (0.60) | PCNATHRBTHRALIG1MEN1 | |
| Hydrochloric Acid SCHEMBL10531318 | 0.76 | MEN1 (0.48) | PCNATHRBTHRAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0078952-B1 | N-AMINOALKYL IODOTHYRONINE DERIVATIVES, IODOTHYRONINE IMMUNOGENS AND ANTIBODIES | MILES LABORATORIES, INC. (US) | 1986-02-26 | — | — | EP | disclosed |
| US-4399121-A | Iodothyronine immunogens and antibodies | MILES LABORATORIES, INC. (US) | 1983-08-16 | — | — | US | disclosed |
| EP-0079489-A1 | Methotrexate-labeled iodothyronine conjugates and method, reagent means and test device for the determination of iodothyronine in or iodothyronine uptake of a liquid sample | MILES LABORATORIES, INC. (US) | 1983-05-25 | — | — | EP | disclosed |
| EP-0078952-A1 | N-aminoalkyl iodothyronine derivatives, iodothyronine immunogens and antibodies | MILES LABORATORIES, INC. (US) | 1983-05-18 | — | — | EP | disclosed |
| US-4358604-A | ANTIBODIES-USEFUL IN IMMUNOASSAY | MILES LABORATORIES, INC. (US) | 1982-11-09 | — | — | US | disclosed |