SCHEMBL188397

SCHEMBL188397

NC(Cc1ccc(Oc2ccc(O)cc2)cc1I)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PCNA P12004 3/20 0.66
THRB P10828 10/20 0.56
THRA P10827 6/20 0.56
MEN1 O00255 6/20 0.56
KMT2A Q03164 6/20 0.56
LMNA P02545 5/20 0.56
PPARG P37231 4/20 0.56
NPSR1 Q6W5P4 2/20 0.56
CYP2D6 P10635 1/20 0.56
TSHR P16473 1/20 0.56
GABRP O00591 1/20 0.56
GABRD O14764 1/20 0.56
ABCB11 O95342 1/20 0.56
F2 P00734 1/20 0.56
GABRA1 P14867 1/20 0.56
GABRB1 P18505 1/20 0.56
GABRG2 P18507 1/20 0.56
GABRB3 P28472 1/20 0.56
ADORA1 P30542 1/20 0.56
GABRA5 P31644 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30693721 1.00 PCNA (0.66) PCNATHRBTHRAMEN1KMT2A
Carbamic Acid SCHEMBL7215408 0.97 PCNA (0.63) PCNATHRBTHRAMEN1KMT2A
Alcohol SCHEMBL5573250 0.95 PCNA (0.60) PCNATHRBTHRAMEN1KMT2A
Sulfuric Acid SCHEMBL8910589 0.95 PCNA (0.60) PCNATHRBTHRAMEN1KMT2A
SCHEMBL10938099 0.87 KMT2A (0.61) PCNATHRBTHRAMEN1KMT2A
SCHEMBL836727 0.87 KMT2A (0.61) PCNATHRBTHRAMEN1KMT2A
SCHEMBL4355962 0.87 KMT2A (0.61) PCNATHRBTHRAMEN1KMT2A
Thyroxine SCHEMBL10886155 0.87 PCNA (0.77) PCNATHRBTHRAMEN1KMT2A
SCHEMBL10880452 0.84 SCN9A (0.48) PCNATHRBTHRAMEN1KMT2A
SCHEMBL1572565 0.84 KDM4E (0.56) PCNATHRBTHRAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1564 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240101963-A1 SC-BETA CELLS AND COMPOSITIONS AND METHODS FOR GENERATING THE SAME PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2024-03-28 US claimed
CN-114540303-A Limbal stem cell culture solution and preparation method thereof 赛尔生命科技(深圳)有限公司 2022-05-27 CN claimed
CN-114302741-A Compositions and methods for treating autoimmune disorders 密执安大学评议会 2022-04-08 CN claimed
EP-3775180-B1 BIOSENSOR FOR DIAGNOSIS OF THYROID DYSFUNCTION AEGIRBIO AB (SE) 2022-01-12 EP claimed
US-20210215723-A1 Biosensor for Diagnosis of Thyroid Dysfunction AEGIRBIO AB (SE) 2021-07-15 US claimed
WO-2021102352-A1 TUMOR ORGANOID CULTURE COMPOSITIONS, SYSTEMS, AND METHODS TEMPUS LABS, INC. (US) 2021-05-27 WO claimed
CN-112437812-A Biosensor for diagnosing thyroid gland dysfunction 埃吉尔比奥公司 2021-03-02 CN claimed
US-10927412-B2 Endometriosis classifier THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-02-23 US claimed
EP-3775180-A1 BIOSENSOR FOR DIAGNOSIS OF THYROID DYSFUNCTION Aegirbio AB (SE) 2021-02-17 EP claimed
CN-111989041-A Vaginal measurements using vaginal rings 里加利私人有限公司 2020-11-24 CN claimed
US-4399121-A Iodothyronine immunogens and antibodies MILES LABORATORIES, INC. (US) 1983-08-16 US claimed
EP-0079489-A1 Methotrexate-labeled iodothyronine conjugates and method, reagent means and test device for the determination of iodothyronine in or iodothyronine uptake of a liquid sample MILES LABORATORIES, INC. (US) 1983-05-25 EP claimed
EP-0078952-A1 N-aminoalkyl iodothyronine derivatives, iodothyronine immunogens and antibodies MILES LABORATORIES, INC. (US) 1983-05-18 EP claimed
EP-0078477-A2 Fenclofenac as TBP blocking agent in iodothyronine immunoassays MILES LABORATORIES, INC. (US) 1983-05-11 EP claimed
EP-0073865-A1 Derivatives of iodothyronine compounds and their use in an assay for the free iodothyronine compounds AMERSHAM INTERNATIONAL plc (GB) 1983-03-16 EP claimed
US-4376165-A Method of preparing an enzyme-labeled ligand for use in specific binding assays and the labeled conjugate produced thereby MILES LABORATORIES, INC. (US) 1983-03-08 US claimed
US-4358604-A ANTIBODIES-USEFUL IN IMMUNOASSAY MILES LABORATORIES, INC. (US) 1982-11-09 US claimed
US-4331808-A Chemiluminescent naphthalene-1,2-dicarboxylic acid hydrazide-labeled haptens MILES LABORATORIES, INC. (US) 1982-05-25 US claimed
US-4238565-A Specific binding assay with a prosthetic group as a label component MILES LABORATORIES, INC. (US) 1980-12-09 US claimed
US-4213893-A Flavin adenine dinucleotide-labeled conjugates for use in specific binding assays MILES LABORATORIES, INC. (US) 1980-07-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240101963-A1 SC-BETA CELLS AND COMPOSITIONS AND METHODS FOR GENERATING THE SAME IAPP, ALPG, PNLIP PCNA 4136/4885THRB 1174/4885THRA 3527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.