Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 6/20 | 0.40 |
| ▸ | REN | P00797 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PEPD | P12955 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8283493 | 1.00 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAHSD17B10CYP2C19RAB9A | |
| Hydrochloric Acid SCHEMBL10877557 | 0.98 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAHSD17B10CYP2C19RAB9A | |
| Hydrochloric Acid SCHEMBL10881267 | 0.98 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAHSD17B10CYP2C19RAB9A | |
| SCHEMBL10878594 | 0.88 | LMNA (0.47) | LMNAHSD17B10CYP2C19RAB9AACE | |
| SCHEMBL28686483 | 0.86 | HRH3 (0.37) | SMN1; SMN2LMNAHSD17B10CYP2C19LTA4H | |
| SCHEMBL5834128 | 0.83 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAHSD17B10CYP2C19RAB9A | |
| SCHEMBL20814097 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAHSD17B10CYP2C19RAB9A | |
| SCHEMBL19022219 | 0.82 | HSD17B10 (0.47) | SMN1; SMN2LMNAHSD17B10CYP2C19RAB9A | |
| SCHEMBL1912615 | 0.82 | HSD17B10 (0.47) | SMN1; SMN2LMNAHSD17B10CYP2C19RAB9A | |
| SCHEMBL16817598 | 0.81 | HSD17B10 (0.46) | SMN1; SMN2LMNAHSD17B10CYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080283-B1 | N-CARBOXYALKYLPROLINE-CONTAINING TRIPEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1986-01-29 | — | — | EP | claimed |