SCHEMBL10882467

SCHEMBL10882467

[CH2]CC(C)=Cc1ccc(OC)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
MAPT P10636 4/20 0.53
KDM4E B2RXH2 4/20 0.53
HPGD P15428 2/20 0.53
CYP3A4 P08684 3/20 0.50
TSHR P16473 2/20 0.50
CYP1A2 P05177 1/20 0.50
NFKB1 P19838 1/20 0.50
APEX1 P27695 1/20 0.50
BLM P54132 1/20 0.50
PMP22 Q01453 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
TUBB1 Q9H4B7 1/20 0.46
CYP2A6 P11509 1/20 0.45
CYP2C9 P11712 1/20 0.45
ALOX15 P16050 1/20 0.45
CYP2C19 P33261 1/20 0.45
GSK3B P49841 1/20 0.44
LMNA P02545 2/20 0.44
TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4630831 0.82 ALDH1A1 (0.55) ALDH1A1MAPTKDM4EHPGDCYP3A4
SCHEMBL1758893 0.82 ALDH1A1 (0.55) ALDH1A1MAPTKDM4EHPGDCYP3A4
SCHEMBL11053464 0.81 ALDH1A1 (0.53) ALDH1A1MAPTKDM4EHPGDCYP3A4
SCHEMBL11053465 0.81 ALDH1A1 (0.53) ALDH1A1MAPTKDM4EHPGDCYP3A4
SCHEMBL1758369 0.81 ALDH1A1 (0.53) ALDH1A1MAPTKDM4EHPGDCYP3A4
SCHEMBL8983605 0.81 ALDH1A1 (0.53) ALDH1A1MAPTKDM4EHPGDCYP3A4
SCHEMBL8144362 0.78 ALDH1A1 (0.50) ALDH1A1MAPTKDM4EHPGDCYP3A4
SCHEMBL11441842 0.78 ALDH1A1 (0.50) ALDH1A1MAPTKDM4EHPGDCYP3A4
SCHEMBL3868301 0.78 ALDH1A1 (0.59) ALDH1A1MAPTKDM4EHPGDCYP3A4
SCHEMBL3868299 0.78 ALDH1A1 (0.59) ALDH1A1MAPTKDM4EHPGDCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0037902-B1 LIQUID CRYSTAL DISPLAY ELEMENT KABUSHIKI KAISHA TOSHIBA (JP) 1986-06-18 EP disclosed