SCHEMBL10883185

SCHEMBL10883185

CCN(CCN(CC)N=O)N=O

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.75
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11525062 0.88
N-Nitrosodiethylamine SCHEMBL8046777 0.86 TSHR (1.00) TSHRALDH1A1
N-Nitrosodiethylamine SCHEMBL106629 0.86
SCHEMBL3341604 0.83
SCHEMBL4562415 0.81 TSHR (0.57) TSHR
SCHEMBL19063242 0.79
N-Nitrosodiethylamine SCHEMBL28087789 0.78 TSHR (0.81) TSHRALDH1A1
SCHEMBL10884326 0.78 TSHR (0.46) TSHR
SCHEMBL11695935 0.77 TSHR (0.52) TSHR
SCHEMBL105573 0.77 TSHR (0.52) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0106453-B1 21-HYDROXYCORTICOSTEROID ESTERS, AND COMPOSITIONS CONTAINING THEM THE UPJOHN COMPANY (US) 1986-10-22 EP claimed
EP-0106453-A1 21-Hydroxycorticosteroid esters, and compositions containing them THE UPJOHN COMPANY (US) 1984-04-25 EP claimed
EP-0106453-B1 21-HYDROXYCORTICOSTEROID ESTERS, AND COMPOSITIONS CONTAINING THEM THE UPJOHN COMPANY (US) 1986-10-22 EP disclosed
US-4456602-A SOLUTION STABLE ANTIINFLAMMATORY AGENTS THE UPJOHN COMPANY (US) 1984-06-26 US disclosed
EP-0106453-A1 21-Hydroxycorticosteroid esters, and compositions containing them THE UPJOHN COMPANY (US) 1984-04-25 EP disclosed