N-Nitrosodiethylamine

N-Nitrosodiethylamine

SCHEMBL8046777

CCN(CC)N=O.CCN(CC)N=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 1.00
ALDH1A1 P00352 1/20 0.38
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Nitrosodiethylamine SCHEMBL106629 1.00
N-Nitrosodiethylamine SCHEMBL28087789 0.90 TSHR (0.81) TSHRALDH1A1
SCHEMBL10883185 0.86 TSHR (0.75) TSHRALDH1A1
SCHEMBL11525062 0.81
SCHEMBL30406839 0.76
SCHEMBL18650271 0.76
SCHEMBL3341604 0.76
N-Nitrosodiethylamine SCHEMBL28052332 0.75 TSHR (0.56) TSHR
SCHEMBL18650461 0.74
SCHEMBL4562415 0.74 TSHR (0.57) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104739917-B Plant extract and application thereof in preparing medicine for treating liver fibrosis and liver cancer 财团法人生物技术开发中心 2019-05-17 CN disclosed
EP-0785186-B1 Process for preparing diels-alder addition product from conjugated diolefin and acrylonitrile MITSUI CHEMICALS INC (JP) 2000-05-31 EP disclosed