Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | HSPA9 | P38646 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NQO2 | P16083 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10882763 | 0.89 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTMEN1KMT2AKDM4A | |
| SCHEMBL10882193 | 0.86 | POLB (0.49) | SMN1; SMN2MAPTMEN1KMT2AKDM4A | |
| SCHEMBL10883795 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTMEN1KMT2AKDM4A | |
| SCHEMBL4603531 | 0.82 | MAPT (0.56) | SMN1; SMN2MAPTMEN1KMT2AKDM4A | |
| SCHEMBL10883259 | 0.77 | POLB (0.47) | SMN1; SMN2MAPTMEN1KMT2AKDM4A | |
| SCHEMBL6468580 | 0.75 | NOX1 (0.50) | SMN1; SMN2MAPTMEN1KMT2AKDM4A | |
| SCHEMBL10882762 | 0.75 | MEN1 (0.48) | SMN1; SMN2MAPTMEN1KMT2AKDM4A | |
| SCHEMBL10695610 | 0.75 | MAPT (0.51) | SMN1; SMN2MAPTMEN1KMT2AKDM4A | |
| SCHEMBL10708746 | 0.74 | MAPT (0.50) | SMN1; SMN2MAPTMEN1KMT2AKDM4A | |
| SCHEMBL10695502 | 0.73 | MAPT (0.49) | SMN1; SMN2MAPTMEN1KMT2AKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0087706-B1 | CATIONIC HYDRAZONE DYES, THEIR MANUFACTURE AND THEIR USE | BAYER AG (DE) | 1986-07-30 | — | — | EP | disclosed |
| US-4496719-A | 3H-Indol-2-yl cationic hydrazone dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1985-01-29 | — | — | US | disclosed |
| EP-0087706-A2 | Cationic hydrazone dyes, their manufacture and their use | BAYER AG (DE) | 1983-09-07 | — | — | EP | disclosed |