Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSPA9 | P38646 | 3/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | GSTO1 | P78417 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4603531 | 0.84 | MAPT (0.56) | SMN1; SMN2ALDH1A1HTTKDM4EHSPA9 | |
| SCHEMBL9091418 | 0.81 | NOX1 (0.51) | NOX1SMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL6408351 | 0.80 | HTT (0.42) | SMN1; SMN2ALDH1A1HTTLMNAKDM4E | |
| SCHEMBL10883262 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1HTTKDM4EHSPA9 | |
| SCHEMBL11443498 | 0.74 | MPI (0.41) | SMN1; SMN2HTTLMNAKDM4EHSPA9 | |
| SCHEMBL9735560 | 0.74 | NR1H2 (0.45) | NOX1SMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL6408346 | 0.73 | ALDH1A1 (0.42) | NOX1SMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL9735977 | 0.71 | PGR (0.44) | ALDH1A1HTTLMNAMEN1MAPT | |
| SCHEMBL10882763 | 0.71 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1HTTKDM4EHSPA9 | |
| SCHEMBL7712511 | 0.70 | CASP3 (0.49) | SMN1; SMN2ALDH1A1HTTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050249668-A1 | Nir-fluorescent cyanine dyes, their synthesis and biological use | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2005-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050249668-A1 | Nir-fluorescent cyanine dyes, their synthesis and biological use | HCCS, MTHFD1, FOLR2 | NOX1 4652/4885SMN1; SMN2 4216/4885ALDH1A1 2739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.