SCHEMBL108845

SCHEMBL108845

CCCC(O)C(O)CC(C)C

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
TSHR P16473 3/20 0.38
ALDH1A1 P00352 1/20 0.36
MAPK1 P28482 1/20 0.36
SPHK1 Q9NYA1 1/20 0.34
CHRM1 P11229 1/20 0.31
AKR1A1 P14550 1/20 0.31
CHRM3 P20309 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31
HRH1 P35367 1/20 0.31
DRD3 P35462 1/20 0.31
SLC6A3 Q01959 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17464928 0.84 LMNA (0.39) LMNATSHRSPHK1
SCHEMBL3927853 0.84 SPHK1 (0.46) LMNATSHRALDH1A1MAPK1SPHK1
SCHEMBL27795695 0.82 SPHK1 (0.56) LMNASPHK1
SCHEMBL104878 0.82 LMNA (0.55) LMNATSHRSPHK1CHRM1AKR1A1
SCHEMBL108359 0.82 TSHR (0.50) LMNATSHRALDH1A1MAPK1TDP1
SCHEMBL13476921 0.82 LMNA (0.55) LMNATSHRSPHK1CHRM1AKR1A1
SCHEMBL9274802 0.81 LMNA (0.41) LMNATSHRSPHK1
SCHEMBL30358249 0.81 METAP1 (0.37) LMNATSHRSPHK1
SCHEMBL8558834 0.81 LMNA (0.46) LMNATSHRSPHK1
SCHEMBL3930118 0.80 SPHK1 (0.59) LMNASPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112521628-B Method for improving transparency of starch-based hydrogel 池州学院 2023-05-30 CN claimed
CN-116041555-A Separation and purification method of amylose and amylose in indica rice 东北农业大学 2023-05-02 CN claimed
CN-112521628-A Method for improving transparency of starch-based hydrogel 池州学院 2021-03-19 CN claimed
CN-105831720-A A preparing method of a lotus seed amylase-aliphatic acid composite having a high composite index number 福建农林大学 2016-08-10 CN claimed
CN-103472057-B A kind of salt compounded of iodine detects liquid fast HARBIN MEDICAL UNIVERSITY (CN) 2015-11-25 CN claimed
CN-103472057-A Rapid iodized salt detection liquid UNIV HARBIN MEDICAL 2013-12-25 CN claimed
EP-2463374-A2 Isolated alcohol dehydrogenase enzymes and uses thereof Bio Architecture Lab, Inc. (US) 2012-06-13 EP claimed
EP-2195440-A2 BIOFUEL PRODUCTION Bio Architecture Lab, Inc. (US) 2010-06-16 EP claimed
US-20090155873-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-18 US claimed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US claimed
WO-2009046370-A2 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-04-09 WO claimed
WO-2009046375-A2 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-04-09 WO claimed
EP-3230463-B2 RAPID PRETREATMENT APALTA PATENTS OUE (EE) 2025-07-16 EP disclosed
US-20240425893-A1 RAPID PRETREATMENT Apalta Patents OÜ (EE) 2024-12-26 US disclosed
US-12054761-B2 Rapid pretreatment Apalta Patents OÜ (EE) 2024-08-06 US disclosed
US-11821047-B2 High pressure zone formation for pretreatment Apalta Patent OÜ (EE) 2023-11-21 US disclosed
US-20090155873-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-18 US disclosed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US disclosed
WO-2009046375-A2 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-04-09 WO disclosed
WO-2009046370-A2 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-04-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090139134-A1 BIOFUEL PRODUCTION MGAM, DCXR, MANBA LMNA 3717/4885TSHR 3426/4885ALDH1A1 753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.