SCHEMBL10885151

SCHEMBL10885151

CCCCCC(CCC)NC

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.42
OPRM1 P35372 1/20 0.40
LMNA P02545 1/20 0.37
DNM1 Q05193 2/20 0.36
ADH1B P00325 1/20 0.35
ADH1C P00326 1/20 0.35
ADH1A P07327 1/20 0.35
ADH4 P08319 1/20 0.35
ADH7 P40394 1/20 0.35
TSHR P16473 2/20 0.35
THRB P10828 1/20 0.35
FDPS P14324 3/20 0.34
GPR84 Q9NQS5 2/20 0.33
ALDH1A1 P00352 1/20 0.33
ZDHHC7 Q9NXF8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21872492 1.00 EPHX1 (0.42) EPHX1OPRM1LMNADNM1ADH1B
SCHEMBL20822491 0.97 EPHX1 (0.46) EPHX1OPRM1LMNADNM1ADH1B
SCHEMBL3838865 0.97 EPHX1 (0.46) EPHX1OPRM1LMNADNM1ADH1B
SCHEMBL28997938 0.97 EPHX1 (0.46) EPHX1OPRM1LMNADNM1ADH1B
SCHEMBL23058658 0.92 DNM1 (0.38) EPHX1LMNADNM1TSHRFDPS
SCHEMBL23851320 0.92 EPHX1 (0.50) EPHX1OPRM1LMNADNM1ADH1B
SCHEMBL24702390 0.92 EPHX1 (0.50) EPHX1OPRM1LMNADNM1ADH1B
SCHEMBL23851606 0.92 EPHX1 (0.50) EPHX1OPRM1LMNADNM1ADH1B
SCHEMBL22344693 0.92 EPHX1 (0.50) EPHX1OPRM1LMNADNM1ADH1B
SCHEMBL25137857 0.92 EPHX1 (0.50) EPHX1OPRM1LMNADNM1ADH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109661229-B Compounds and compositions for the treatment of cancer 加利福尼亚大学董事会 2022-06-28 CN disclosed
EP-3373937-B1 ANTI-CD22 ANTIBODY-MAYTANSINE CONJUGATES AND METHODS OF USE THEREOF SCHERER TECHNOLOGIES LLC R P (US) 2021-12-22 EP disclosed
US-20120328863-A1 Silicone-Based Releasable Adhesive Composition, Sheet-Form Substrate Having Releasable Adhesive Layer Formed By Curing This Composition, And Use Of Such A Protective Film Or Fixing Sheet DOW CORNING TORAY CO., LTD. (JP) 2012-12-27 US disclosed
EP-2524954-A1 RE-ADHERABLE SILICONE-BASED ADHESIVE COMPOSITION, SHEET-SHAPED BASE MATERIAL HAVING RE-ADHERABLE ADHESIVE LAYER OBTAINED BY CURING SAID COMPOSITION, AND USE OF SAID BASE MATERIAL AS PROTECTIVE FILM OR AFFIXING SHEET Dow Corning Toray Co., Ltd. (JP) 2012-11-21 EP disclosed
EP-0206621-A1 Process for disproportionating silanes MITSUI TOATSU CHEMICALS, Inc. (JP) 1986-12-30 EP disclosed