Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | DPP4 | P27487 | 2/20 | 0.52 |
| ▸ | FAP | Q12884 | 2/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.52 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.52 |
| ▸ | TPH1 | P17752 | 2/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.45 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10885375 | 1.00 | LDHA (0.59) | LDHASLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL4655986 | 0.86 | LDHA (0.62) | LDHASLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL13113076 | 0.86 | LDHA (0.62) | LDHASLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL12104023 | 0.86 | LDHA (0.62) | LDHASLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL158667 | 0.84 | LDHA (0.71) | LDHASLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL126195 | 0.84 | LDHA (0.71) | LDHASLC6A4CYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL11833376 | 0.84 | LDHA (0.61) | LDHASLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL597743 | 0.84 | LDHA (0.71) | LDHASLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1587131 | 0.84 | LDHA (0.61) | LDHASLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1587128 | 0.84 | LDHA (0.61) | LDHASLC6A4CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071926-B1 | NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-08 | — | — | EP | claimed |
| EP-0071926-B1 | NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-08 | — | — | EP | disclosed |
| US-4479942-A | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |