SCHEMBL10885674

SCHEMBL10885674

CCCCCCc1cc(CCCCCC)c(O)c(CCCCCC)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 8/20 0.64
CYP3A4 P08684 3/20 0.61
ALOX5 P09917 5/20 0.54
ESR1 P03372 2/20 0.53
ADRA2A P08913 2/20 0.53
ADORA3 P0DMS8 2/20 0.53
TACR2 P21452 2/20 0.53
SLC6A2 P23975 2/20 0.53
SLC6A4 P31645 2/20 0.53
SLC6A3 Q01959 2/20 0.53
TP53 P04637 2/20 0.53
KDM4E B2RXH2 1/20 0.53
ALDH1A1 P00352 1/20 0.53
LMNA P02545 1/20 0.53
SHBG P04278 1/20 0.53
HSPD1 P10809 1/20 0.53
ADRB3 P13945 1/20 0.53
HTR2C P28335 1/20 0.53
HSPE1 P61604 1/20 0.53
HIF1A Q16665 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17965866 1.00 PTGS2 (0.64) PTGS2CYP3A4ALOX5ESR1ADRA2A
SCHEMBL15867510 1.00 PTGS2 (0.64) PTGS2CYP3A4ALOX5ESR1ADRA2A
SCHEMBL15867513 1.00 PTGS2 (0.64) PTGS2CYP3A4ALOX5ESR1ADRA2A
SCHEMBL199837 1.00 PTGS2 (0.64) PTGS2CYP3A4ALOX5ESR1ADRA2A
SCHEMBL4969327 1.00 PTGS2 (0.64) PTGS2CYP3A4ALOX5ESR1ADRA2A
SCHEMBL199535 1.00 PTGS2 (0.64) PTGS2CYP3A4ALOX5ESR1ADRA2A
SCHEMBL202874 1.00 PTGS2 (0.64) PTGS2CYP3A4ALOX5ESR1ADRA2A
SCHEMBL11806112 1.00 PTGS2 (0.64) PTGS2CYP3A4ALOX5ESR1ADRA2A
SCHEMBL201605 1.00 PTGS2 (0.64) PTGS2CYP3A4ALOX5ESR1ADRA2A
SCHEMBL27980726 1.00 PTGS2 (0.64) PTGS2CYP3A4ALOX5ESR1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9795549-B2 1,2-alkane polyol-containing composition OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) 2017-10-24 US disclosed
US-20160045414-A1 1,2-ALKANE POLYOL-CONTAINING COMPOSITION OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) 2016-02-18 US disclosed
EP-2985017-A1 1,2-ALKANE POLYOL-CONTAINING COMPOSITION Osaka Organic Chemical Ind., Ltd. (JP) 2016-02-17 EP disclosed
CN-103709442-B Stabilizer and composition comprising the same Double bond chemical (Shanghai) Co.,Ltd. (CN) 2016-01-06 CN disclosed
CN-105142605-A 1, 2-alkane polyol-containing composition OSAKA ORGANIC CHEM IND 2015-12-09 CN disclosed
CN-104704024-A Methods of manufacture of bis(phthalimide)s and polyetherimides, and bis(phthalimide)s, and polyetherimides formed therefrom SABIC INNOVATIVE PLASTICS IP 2015-06-10 CN disclosed
CN-104520351-A Polyetherimide compositions, methods of manufacture, and articles formed therefrom SABIC INNOVATIVE PLASTICS IP 2015-04-15 CN disclosed
EP-0122203-B1 (HYDROCARBYLTHIO)PHENOLS AND THEIR PREPARATION ETHYL CORPORATION (US) 1986-12-30 EP disclosed
US-4602113-A (Hydrocarbylthio) phenols and their preparation ETHYL CORPORATION (US) 1986-07-22 US disclosed
WO-1984004092-A1 (HYDROCARBYLTHIO)PHENOLS AND THEIR PREPARATION ETHYL CORP (US) 1984-10-25 WO disclosed
US-4287928-A Puncture-sealing tire THE B. F. GOODRICH COMPANY (US) 1981-09-08 US disclosed
US-4284742-A Puncture-sealing tire THE B. F. GOODRICH COMPANY (US) 1981-08-18 US disclosed
US-4263075-A Method of making a puncture-sealing tire with sealant consisting of a vinylidene-terminated liquid polymer and an amine THE B. F. GOODRICH COMPANY (US) 1981-04-21 US disclosed
US-4255538-A ADDITION POLYMERS AND POLYETHERS MODIFIED BY UNSATURATED EPOXY COMPOUNDS; HIGH SPEED CURING TO SOLID ELASTOMERS THE B. F. GOODRICH COMPANY (US) 1981-03-10 US disclosed
US-4216302-A GLYCIDYL ACRYLATE TERMINATED POLYETHER USEFUL AS SEALANTS CAULKS, POTTING COMPOUNDS AND COATINGS THE B. F. GOODRICH COMPANY (US) 1980-08-05 US disclosed
US-4214619-A Puncture-sealing tire THE B. F. GOODRICH COMPANY (US) 1980-07-29 US disclosed
US-4147854-A GLYCIDYL ACRYLATE, CARBOXY-TERMINATED DIENE-NITRILE COPOLYMERS THE B. F. GOODRICH COMPANY (US) 1979-04-03 US disclosed
US-4129713-A ACRYLATE THE B. F. GOODRICH COMPANY (US) 1978-12-12 US disclosed
US-4058657-A Co-cured compositions of amine-terminated liquid polymers and vinylidene-terminated polymers and process for preparation thereof THE B. F. GOODRICH COMPANY (US) 1977-11-15 US disclosed
US-4013710-A ELASTOMERS, SEALANTS, CAULKS, POTTING, COATINGS THE B. F. GOODRICH COMPANY (US) 1977-03-22 US disclosed