SCHEMBL10885707

SCHEMBL10885707

Ic1cc2nc[nH]c2cc1I

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.56
KDM4E B2RXH2 4/20 0.56
ALDH1A1 P00352 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
APEX1 P27695 1/20 0.56
RECQL P46063 1/20 0.56
BLM P54132 1/20 0.56
PRKCI P41743 1/20 0.47
RAD52 P43351 1/20 0.45
CHRNB2 P17787 1/20 0.43
CHRNA4 P43681 1/20 0.43
MMP12 P39900 1/20 0.42
CYP3A4 P08684 1/20 0.41
NAMPT P43490 1/20 0.41
XDH P47989 1/20 0.41
QPCT Q16769 4/20 0.40
QPCTL Q9NXS2 2/20 0.40
HDAC6 Q9UBN7 1/20 0.38
PARP1 P09874 1/20 0.37
PKM P14618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14154810 0.85 MAPT (0.63) MAPTKDM4EALDH1A1TDP1APEX1
SCHEMBL30490133 0.85 MAPT (0.63) MAPTKDM4EALDH1A1TDP1APEX1
SCHEMBL30390007 0.83 MAPT (0.61) MAPTKDM4EALDH1A1TDP1APEX1
SCHEMBL10884699 0.83 MAPT (0.70) MAPTKDM4EALDH1A1TDP1APEX1
SCHEMBL2317068 0.83 MAPT (0.67) MAPTKDM4EALDH1A1TDP1APEX1
SCHEMBL2317063 0.83 MAPT (0.61) MAPTKDM4EALDH1A1TDP1APEX1
SCHEMBL10884689 0.83 MAPT (0.70) MAPTKDM4EALDH1A1TDP1APEX1
SCHEMBL14511179 0.82 MAPT (0.68) MAPTKDM4EALDH1A1TDP1APEX1
SCHEMBL12445185 0.79 MAPT (0.65) MAPTKDM4EALDH1A1TDP1APEX1
SCHEMBL1266091 0.76 MAPT (0.70) MAPTKDM4EALDH1A1TDP1APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10756394-B2 Nonaqueous electrolyte and nonaqueous secondary battery ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-08-25 US disclosed
US-20180062213-A1 Nonaqueous Electrolyte and Nonaqueous Secondary Battery ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-03-01 US disclosed
US-20180062213-A1 Nonaqueous Electrolyte and Nonaqueous Secondary Battery ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-03-01 US disclosed
EP-3279997-A1 NONAQUEOUS ELECTROLYTE AND NONAQUEOUS SECONDARY BATTERY Asahi Kasei Kabushiki Kaisha (JP) 2018-02-07 EP disclosed
EP-0088595-B1 CYANINE DYES FOR SENSITIZING SILVER HALIDE EMULSIONS TO INFRARED RADIATION AND PHOTOGRAPHIC ELEMENTS INCLUDING THEM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-09-24 EP disclosed
US-4515888-A BASED ON 5-METHYL-6-METHOXYBENZOTHIAZOLE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-05-07 US disclosed
EP-0088595-A2 Cyanine dyes for sensitizing silver halide emulsions to infrared radiation and photographic elements including them MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-09-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10756394-B2 Nonaqueous electrolyte and nonaqueous secondary battery BPTF, BRD4, KCNN2 MAPT 1283/4885KDM4E 2256/4885ALDH1A1 3497/4885
US-20180062213-A1 Nonaqueous Electrolyte and Nonaqueous Secondary Battery BPTF, BRD4, KCNN2 MAPT 1283/4885KDM4E 2256/4885ALDH1A1 3497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.