SCHEMBL12445185

SCHEMBL12445185

c1nc2cc3nc[nH]c3cc2[nH]1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.65
KDM4E B2RXH2 4/20 0.65
ALDH1A1 P00352 2/20 0.65
TDP1 Q9NUW8 2/20 0.65
APEX1 P27695 1/20 0.65
RECQL P46063 1/20 0.65
BLM P54132 1/20 0.65
PRKCI P41743 1/20 0.54
RAD52 P43351 1/20 0.52
CHRNB2 P17787 1/20 0.48
CHRNA4 P43681 1/20 0.48
MMP12 P39900 1/20 0.48
CYP3A4 P08684 1/20 0.47
NAMPT P43490 1/20 0.47
XDH P47989 1/20 0.47
HDAC6 Q9UBN7 1/20 0.42
QPCT Q16769 4/20 0.41
QPCTL Q9NXS2 4/20 0.41
PKM P14618 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14511179 0.91 MAPT (0.68) MAPTKDM4EALDH1A1TDP1APEX1
SCHEMBL2136974 0.85 MAPT (0.56) MAPTKDM4EALDH1A1TDP1APEX1
SCHEMBL10885707 0.79 MAPT (0.56) MAPTKDM4EALDH1A1TDP1APEX1
SCHEMBL8370769 0.79 MAPT (0.56) MAPTKDM4EALDH1A1TDP1APEX1
SCHEMBL352396 0.79 MAPT (0.70) MAPTKDM4EALDH1A1TDP1APEX1
SCHEMBL11206398 0.79 MAPT (0.50) MAPTKDM4EALDH1A1TDP1APEX1
SCHEMBL9703253 0.79 MAPT (0.50) MAPTKDM4EALDH1A1TDP1APEX1
SCHEMBL7076189 0.78 MKNK1 (0.56) MAPTKDM4EALDH1A1TDP1APEX1
SCHEMBL4498108 0.78 MAPT (0.48) MAPTKDM4EALDH1A1TDP1APEX1
SCHEMBL15010385 0.78 KDM4E (0.48) MAPTKDM4EALDH1A1TDP1APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12565613-B2 Quantum dots with donor-acceptor ligands SHOEI CHEMICAL INC. (JP) 2026-03-03 US disclosed
WO-2024219401-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2024-10-24 WO disclosed
US-20230036119-A1 QUANTUM DOTS WITH DONOR-ACCEPTOR LIGANDS NANOSYS, INC. 2023-02-02 US disclosed
US-20230036119-A1 QUANTUM DOTS WITH DONOR-ACCEPTOR LIGANDS NANOSYS, INC. 2023-02-02 US disclosed
US-11527730-B2 Organic electroluminescence device and organometallic complex for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2022-12-13 US disclosed
US-11008291-B2 Methods of forming carbene-functionalized composite materials QUEEN'S UNIVERSITY AT KINGSTON (CA) 2021-05-18 US disclosed
US-20200373504-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANOMETALLIC COMPLEX FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-11-26 US disclosed
US-20190169132-A1 Methods of Forming Carbene-Functionalized Composite Materials QUEEN'S UNIVERSITY AT KINGSTON (CA) 2019-06-06 US disclosed
WO-2017075704-A1 METHODS OF FORMING CARBENE-FUNCTIONALIZED COMPOSITE MATERIALS QUEEN'S UNIVERSITY AT KINGSTON (CA) 2017-05-11 WO disclosed
US-8753542-B2 Thermally stable conducting polymers, methods of making, and methods of use thereof THE UNIVERSITY OF CONNECTICUT (US) 2014-06-17 US disclosed
US-8753542-B2 Thermally stable conducting polymers, methods of making, and methods of use thereof THE UNIVERSITY OF CONNECTICUT (US) 2014-06-17 US disclosed
WO-2011088010-A2 THERMALLY STABLE CONDUCTING POLYMERS, METHODS OF MAKING, AND METHODS OF USE THEREOF UNIVERSITY OF CONNECTICUT (US) 2011-07-21 WO disclosed
US-20110168951-A1 THERMALLY STABLE CONDUCTING POLYMERS, METHODS OF MAKING, AND METHODS OF USE THEREOF THE UNIVERSITY OF CONNECTICUT 2011-07-14 US disclosed
US-20110168951-A1 THERMALLY STABLE CONDUCTING POLYMERS, METHODS OF MAKING, AND METHODS OF USE THEREOF THE UNIVERSITY OF CONNECTICUT 2011-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11008291-B2 Methods of forming carbene-functionalized composite materials VCL, CHN2, CA3 MAPT 4362/4885KDM4E 4231/4885ALDH1A1 2011/4885
US-12565613-B2 Quantum dots with donor-acceptor ligands HCCS, FDPS, FTH1 MAPT 3930/4885KDM4E 4066/4885ALDH1A1 125/4885
US-20190169132-A1 Methods of Forming Carbene-Functionalized Composite Materials VCL, CHN2, CA3 MAPT 4362/4885KDM4E 4231/4885ALDH1A1 2011/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.