Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 4/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.76 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gyki-52466 SCHEMBL194854 | 0.86 | GRIA2 (1.00) | GRIA2MEN1CYP1A2CYP3A4CYP2D6 | |
| Gyki-52466 SCHEMBL29357520 | 0.86 | GRIA2 (1.00) | GRIA2MEN1CYP1A2CYP3A4CYP2D6 | |
| Gyki-52466 SCHEMBL25227675 | 0.85 | LMNA (1.00) | GRIA2MEN1CYP1A2CYP3A4CYP2D6 | |
| Gyki-52466 SCHEMBL249675 | 0.85 | LMNA (1.00) | GRIA2MEN1CYP1A2CYP3A4CYP2D6 | |
| Gyki-52466 SCHEMBL29651319 | 0.85 | LMNA (1.00) | GRIA2MEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5048632 | 0.80 | GRIA2 (0.67) | GRIA2MEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10887682 | 0.79 | CYP1A2 (0.47) | GRIA2MEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6625251 | 0.76 | GRIA2 (0.66) | GRIA2MEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10893573 | 0.76 | CYP3A4 (0.45) | GRIA2MEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7492463 | 0.74 | MAPT (0.69) | GRIA2MEN1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4614740-A | NERVOUS SYSTEM DISORDERS | EGIS GYOGYSZERGYAR (HU) | 1986-09-30 | — | — | US | disclosed |