Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10890436 | 0.82 | CA12 (0.46) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL10892587 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL17786624 | 0.76 | MAPT (0.52) | ALDH1A1MAPTKDM4ECA12CA1 | |
| SCHEMBL10890144 | 0.75 | TNKS (0.61) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL14020467 | 0.74 | ALDH1A1 (0.85) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL14020471 | 0.73 | ALDH1A1 (0.79) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL1422852 | 0.72 | ALDH1A1 (0.78) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL490587 | 0.72 | TTR (0.62) | ALDH1A1NPC1RAB9AKDM4ECA12 | |
| SCHEMBL10885986 | 0.72 | MAPT (0.48) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL17786434 | 0.72 | KDM4E (0.62) | ALDH1A1MAPTNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4600788-A | ANTIDIABETIC AGENTS, DIURETICS/ ALYST, ENAMINE | SOCIETE CORTIAL, S.A. (FR) | 1986-07-15 | — | — | US | disclosed |