Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GRK6 | P43250 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10887128 | 0.84 | PDE3B (0.42) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10889047 | 0.81 | PDE3B (0.52) | ALDH1A1PDE3BPDE3APDE4APDE4B | |
| SCHEMBL10368593 | 0.81 | PDE3B (0.62) | ALDH1A1PDE3BPDE3APDE4APDE4B | |
| SCHEMBL16157003 | 0.81 | PDE3B (0.62) | ALDH1A1PDE3BPDE3APDE4APDE4B | |
| SCHEMBL17446935 | 0.79 | PDE3B (0.48) | AKR1C3ALDH1A1PDE3BPDE3APDE4A | |
| SCHEMBL16157010 | 0.78 | PDE3B (0.61) | ALDH1A1PDE3BPDE3APDE4APDE4B | |
| SCHEMBL10891315 | 0.76 | PDE3B (0.67) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL7295733 | 0.74 | PDE3B (0.52) | ALDH1A1PDE3BPDE3APDE4APDE4B | |
| SCHEMBL10887841 | 0.74 | PDE3B (0.47) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL10886219 | 0.73 | APP (0.56) | ALDH1A1PDE3BPDE3APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4616015-A | HYPOTENSIVE AGENT, ANTULCER AGENT, ANTICOAGULANT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-07 | — | — | US | disclosed |
| EP-0122627-A2 | Triazine derivatives, processes for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-24 | — | — | EP | disclosed |