Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.60 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10885166 | 0.88 | ACE (0.64) | ACEF2F10 | |
| SCHEMBL10404199 | 0.81 | SMN1; SMN2 (0.52) | ACELMNA | |
| SCHEMBL11225012 | 0.80 | ACE (0.68) | ACE | |
| SCHEMBL27890165 | 0.79 | ACE (0.73) | ACEF2LMNA | |
| SCHEMBL27890164 | 0.79 | ACE (0.73) | ACEF2LMNA | |
| SCHEMBL10679400 | 0.78 | ACE (0.66) | ACE | |
| SCHEMBL28803852 | 0.77 | ACE (0.64) | ACEF2 | |
| SCHEMBL17660482 | 0.77 | ACE (0.75) | ACEF2LMNA | |
| SCHEMBL27890161 | 0.77 | ACE (0.75) | ACEF2LMNA | |
| SCHEMBL27890166 | 0.77 | ACE (0.75) | ACEF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0190852-A2 | Dipeptide derivatives and antihypertensive drugs containing them | AJINOMOTO CO., INC. (JP) | 1986-08-13 | — | — | EP | disclosed |