Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26859096 | 0.79 | HCAR2 (0.35) | HCAR2 | |
| SCHEMBL26859996 | 0.78 | HCAR2 (0.34) | HCAR2 | |
| SCHEMBL21389734 | 0.76 | HCAR2 (0.39) | HCAR2NOS1 | |
| SCHEMBL12058917 | 0.76 | HCAR2 (0.39) | HCAR2NOS1 | |
| SCHEMBL5121295 | 0.73 | HCAR2 (0.40) | HCAR2NOS1 | |
| SCHEMBL20206550 | 0.72 | HCAR2 (0.33) | HCAR2 | |
| SCHEMBL3439423 | 0.72 | LOXL2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL568484 | 0.71 | LOXL2 (0.33) | — | |
| SCHEMBL21209899 | 0.70 | HCAR2 (0.38) | HCAR2 | |
| SCHEMBL13886980 | 0.70 | HCAR2 (0.42) | HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4600025-A | 2-METHYL-5(HETEROMETHYL)THIAZOLE | GRIGG RONALD E | 1986-07-15 | — | — | US | disclosed |
| EP-0034481-A1 | 2-Methyl-5-thiazole-methylamine and carboxamide derivatives | Grigg, Ronald Ernest (GB) | 1981-08-26 | — | — | EP | disclosed |