Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 12/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.50 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.50 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.49 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10890506 | 1.00 | BACE1 (0.52) | BACE1DPP4DPP8DPP9BACE2 | |
| SCHEMBL31064913 | 0.97 | DPP4 (0.52) | BACE1DPP4DPP8DPP9BACE2 | |
| SCHEMBL30905101 | 0.96 | DPP4 (0.54) | BACE1DPP4DPP8DPP9BACE2 | |
| SCHEMBL29843968 | 0.96 | DPP4 (0.54) | BACE1DPP4DPP8DPP9BACE2 | |
| SCHEMBL3178877 | 0.95 | PTPN1 (0.52) | BACE1DPP4DPP8DPP9BACE2 | |
| SCHEMBL22315779 | 0.95 | PTPN1 (0.52) | BACE1DPP4DPP8DPP9BACE2 | |
| SCHEMBL9293719 | 0.95 | BACE1 (0.51) | BACE1DPP4DPP8DPP9BACE2 | |
| SCHEMBL9293727 | 0.95 | BACE1 (0.51) | BACE1DPP4DPP8DPP9BACE2 | |
| SCHEMBL3178856 | 0.95 | PTPN1 (0.52) | BACE1DPP4DPP8DPP9BACE2 | |
| SCHEMBL29591098 | 0.92 | ENPEP (0.46) | BACE1DPP4DPP8DPP9BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4590003-A | ANTITUMOR AGENT | ONCOGEN (US) | 1986-05-20 | — | — | US | claimed |