Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL1053204 | 0.97 | ALDH1A1 (0.48) | ALDH1A1CYP3A4KDM4ALMNAGAA | |
| SCHEMBL11180477 | 0.97 | ALDH1A1 (0.48) | ALDH1A1CYP3A4KDM4ALMNAGAA | |
| SCHEMBL711225 | 0.95 | ALDH1A1 (0.50) | ALDH1A1CYP3A4KDM4ALMNAGAA | |
| SCHEMBL503606 | 0.95 | ALDH1A1 (0.50) | ALDH1A1CYP3A4KDM4ALMNAGAA | |
| SCHEMBL29143167 | 0.92 | ALDH1A1 (0.48) | ALDH1A1CYP3A4KDM4ALMNAGAA | |
| Water SCHEMBL5200164 | 0.92 | ALDH1A1 (0.48) | ALDH1A1CYP3A4KDM4ALMNAGAA | |
| SCHEMBL15611174 | 0.92 | ALDH1A1 (0.48) | ALDH1A1CYP3A4KDM4ALMNAGAA | |
| SCHEMBL9420825 | 0.92 | ALDH1A1 (0.48) | ALDH1A1CYP3A4KDM4ALMNAGAA | |
| Selenium SCHEMBL11484547 | 0.92 | ALDH1A1 (0.48) | ALDH1A1CYP3A4KDM4ALMNAGAA | |
| Benzene SCHEMBL28837687 | 0.90 | ALDH1A1 (0.46) | ALDH1A1CYP3A4KDM4ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4594238-A | Administering platinum compound; then platimun binding compound | REGENTS OF UNIVERSITY OF MINNESOTA (US) | 1986-06-10 | — | — | US | disclosed |
| US-4581224-A | ANTITUMOR, ANTRICARCINOGENIC AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1986-04-08 | — | — | US | disclosed |