SCHEMBL108923

SCHEMBL108923

O=C=Nc1ccc(C(N=C=O)c2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TRPA1 O75762 1/20 0.34
MIF P14174 4/20 0.33
CYP2D6 P10635 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5537030 0.92 CYP3A4 (0.48) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL16628653 0.91 TSHR (0.33) CYP3A4TSHRMIF
SCHEMBL134389 0.86 MIF (0.40) TSHRMAPK1TRPA1MIFCYP2D6
SCHEMBL8853885 0.84 CYP3A4 (0.39) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL1205494 0.84 MIF (0.39) TSHRMAPK1TRPA1MIFCYP2D6
SCHEMBL295315 0.82 CYP3A4 (0.47) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL11452983 0.81 CYP3A4 (0.39) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL28839465 0.80 MIF (0.36) TSHRMAPK1TRPA1MIFCYP2D6
SCHEMBL27268705 0.80 MIF (0.36) TSHRMAPK1TRPA1MIFCYP2D6
SCHEMBL10635550 0.80 CYP3A4 (0.38) CYP3A4TSHRMAPK1TDP1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5084 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118341173-A Filter bag with welding agent material and preparation method thereof 江苏奥凯环境技术有限公司 2024-07-16 CN claimed
CN-118344552-A 3D printing thermoplastic polyurethane material with high damping performance at normal temperature and preparation method thereof 上海交通大学 2024-07-16 CN claimed
CN-118355088-A Moisture-curable polyurethane hot melt adhesive compositions 汉高股份有限及两合公司 2024-07-16 CN claimed
CN-118307759-A Preparation method of degradable PBAT polyester 万华化学集团股份有限公司 2024-07-09 CN claimed
CN-118291076-A Double-component solvent-free polyurethane adhesive and preparation method thereof 黄山市天马科技有限公司 2024-07-05 CN claimed
CN-118290690-A Thermoplastic polyurethane for large-caliber extrusion and preparation method thereof 万华化学集团股份有限公司 2024-07-05 CN claimed
CN-118290696-A High-strength high-toughness carbon dioxide-based polyester, and preparation method and application thereof 江南大学 2024-07-05 CN claimed
CN-118085214-B Preparation method of polyurethane association type thickener 烟台云泷化学制品有限公司 2024-07-02 CN claimed
CN-115028966-B Wide temperature range thermoplastic super-tough elastomer resin composition 马佩瑶 2024-07-02 CN claimed
CN-118265317-A Light-emitting device, preparation method thereof and display device 广东聚华印刷显示技术有限公司 2024-06-28 CN claimed
EP-0865458-A1 POLYURETHANE ELASTOMERS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1998-09-23 EP claimed
EP-0846142-A1 INTERNAL MOLD RELEASE COMPOSITIONS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1998-06-10 EP claimed
WO-1997021750-A1 POLYURETHANE ELASTOMERS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1997-06-19 WO claimed
WO-1997008234-A1 INTERNAL MOLD RELEASE COMPOSITIONS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1997-03-06 WO claimed
EP-0526123-B1 Curable compositions based on unsaturated isocyanurate resins ASHLAND OIL INC (US) 1996-12-18 EP claimed
WO-1996036676-A1 PROCESS FOR PRODUCTION OF MULTI-LAYER COMPOSITE ARTICLE DAVIDSON TEXTRON INC. (US) 1996-11-21 WO claimed
WO-1995009201-A1 POLYEUREA MODIFIED UNSATURATED POLYESTER COMPOSITIONS CAMBRIDGE INDUSTRIES, INC. (US) 1995-04-06 WO claimed
EP-0416762-B1 Cationic electrodeposition paint composition NISSAN MOTOR (JP) 1994-06-15 EP claimed
CN-1087919-A Polymer-modified polyol dispersions and production method thereof and purposes WOODBRIDGE FOAM CORP (CA) 1994-06-15 CN claimed
US-5232970-A High strength, heat and moisture resistance, flexibility, dielectric for encapsulation of circuits THE DOW CHEMICAL COMPANY (US) 1993-08-03 US claimed