SCHEMBL134389

SCHEMBL134389

O=C=NC(c1ccccc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MIF P14174 3/20 0.40
CYP2D6 P10635 1/20 0.37
SRC P12931 1/20 0.37
DPP4 P27487 2/20 0.36
TSHR P16473 2/20 0.36
F2 P00734 1/20 0.36
LMNA P02545 2/20 0.36
MAPK1 P28482 1/20 0.36
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
TRPA1 O75762 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1205494 0.98 MIF (0.39) MIFCYP2D6SRCDPP4TSHR
SCHEMBL28839465 0.93 MIF (0.36) MIFCYP2D6SRCDPP4TSHR
SCHEMBL27268705 0.93 MIF (0.36) MIFCYP2D6SRCDPP4TSHR
SCHEMBL7634319 0.89 MIF (0.36) MIFCYP2D6SRCDPP4TSHR
SCHEMBL11204933 0.88 LMNA (0.42) MIFTSHRLMNACES2CES1
SCHEMBL9833550 0.87 ACP3 (0.42) MAPK1
SCHEMBL108923 0.86 CYP3A4 (0.42) MIFCYP2D6TSHRMAPK1TRPA1
SCHEMBL16628653 0.84 TSHR (0.33) MIFTSHR
SCHEMBL8853885 0.82 CYP3A4 (0.39) MIFCYP2D6TSHRMAPK1TRPA1
SCHEMBL20146 0.80 MIF (0.40) MIFCYP2D6SRCDPP4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1618 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4074481-B1 METHOD OF COATING A PANEL-SHAPED WORKPIECE SWISS KRONO Tec AG (CH) 2026-01-28 EP claimed
EP-3529319-B1 RHEOLOGY-MODIFYING URETHANE COMPOUND COATEX SAS (FR) 2025-07-30 EP claimed
CN-120025777-A High-cohesiveness polyol polyurethane adhesive, and preparation method and application thereof 安徽创园体育科技有限公司 2025-05-23 CN claimed
CN-119978290-A Polyurethane of bio-based polyether polyol and preparation method thereof 河北博伊德化工有限公司 2025-05-13 CN claimed
CN-119081042-A Polyurethane foaming material introduced with rigid molecular chain and preparation method thereof 合肥工业大学 2024-12-06 CN claimed
CN-118922284-A Method for producing particle board and particle board 瑞士克罗诺泰克股份公司 2024-11-08 CN claimed
CN-118530694-A Construction method for structural layer and adaptation with interlayer bonding enhancement function 山东省交通科学研究院 2024-08-23 CN claimed
CN-118496471-A Preparation method of polyurethane foam material 万华化学集团股份有限公司 2024-08-16 CN claimed
CN-117962365-B Preparation method for equal-diameter polyurethane composite material communication rod through pultrusion, braiding and winding 黑龙江大学 2024-08-16 CN claimed
CN-118256030-A Carbon material composite hydrogenated nitrile/fluororubber alloy composition, alloy elastomer and preparation method and application thereof 中国石油化工股份有限公司 2024-06-28 CN claimed
EP-0418686-A2 Thermoplastic polymer mixture from polyurethane and ABS and process for their preparation BAYER AG (DE) 1991-03-27 EP claimed
CN-1047871-A POLYISOCYANURATE FOAM WALTER JIM RES CORP (US) 1990-12-19 CN claimed
US-4952358-A POLYISOCYANURATES FROM POLYOLS AND POLYISOCYANATES, REINFORCEMENT FIBER AND TRIMERIZATION CATALYST INOUE MTP KABUSHIKI KAISHA (JP) 1990-08-28 US claimed
EP-0344551-A2 Liquid polyisocyanate mixtures, process for their preparation and their use in the preparation of flexible polyurethane foams BAYER AG (DE) 1989-12-06 EP claimed
US-4613687-A POLYURETHANES BAYER AKTIENGESELLSCHAFT (DE) 1986-09-23 US claimed
EP-0046917-B1 POLYISOCYANATE MIXTURES OF THE DIPHENYLMETHANE CLASS, AS WELL AS THEIR USE AS SYNTHESIS COMPONENTS IN THE MANUFACTURE OF POLYURETHANES BY THE ISOCYANATE-POLYADDITION PROCESS BAYER AG (DE) 1983-12-07 EP claimed
EP-0019844-B1 SURFACE-ACTIVE AGENTS, AQUEOUS ISOCYANATE EMULSIONS CONTAINING THESE SURFACE-ACTIVE AGENTS, AND THEIR USE AS BINDERS FOR MANUFACTURING MOULDED BODIES BAYER AG (DE) 1983-03-16 EP claimed
US-4286001-A Process for the production of industrial parts of synthetic material comprising a rigid portion surmounted by a flexible portion and the industrial part produced by said process LES MANUFACTURES DE SAINT MARCEL (FR) 1981-08-25 US claimed
EP-0000893-A1 Process for the preparation of polyisocyanates and their use BAYER AG (DE) 1979-03-07 EP claimed
US-3947426-A Solid particle-form polymerizable polymeric material and compositions, structures and methods of employing and producing the same STORY CHEMICAL CORPORATION (US) 1976-03-30 US claimed