Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.64 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.61 |
| ▸ | PPARG | P37231 | 7/20 | 0.61 |
| ▸ | PPARD | Q03181 | 7/20 | 0.61 |
| ▸ | PPARA | Q07869 | 7/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TLR2 | O60603 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | FABP4 | P15090 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.61 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL28405433 | 0.98 | AKR1B1 (0.61) | AKR1B1GPR84PPARGPPARDPPARA | |
| Tetrabuthylammonium SCHEMBL106829 | 0.93 | AKR1B1 (0.68) | AKR1B1GPR84PPARGPPARDPPARA | |
| Tetrabuthylammonium SCHEMBL27680107 | 0.93 | FFAR3 (0.62) | AKR1B1GPR84PPARGPPARDPPARA | |
| Tetrabuthylammonium SCHEMBL1716569 | 0.93 | AKR1B1 (0.76) | AKR1B1GPR84PPARGPPARDPPARA | |
| Tetrabuthylammonium SCHEMBL109357 | 0.93 | AKR1B1 (0.68) | AKR1B1GPR84PPARGPPARDPPARA | |
| Tetrabuthylammonium SCHEMBL104376 | 0.93 | AKR1B1 (0.76) | AKR1B1GPR84PPARGPPARDPPARA | |
| Tetrabuthylammonium SCHEMBL5574260 | 0.93 | AKR1B1 (0.68) | AKR1B1GPR84PPARGPPARDPPARA | |
| Tetrabuthylammonium SCHEMBL106024 | 0.93 | AKR1B1 (0.76) | AKR1B1GPR84PPARGPPARDPPARA | |
| Tetrabuthylammonium SCHEMBL2230012 | 0.91 | GPR84 (0.77) | AKR1B1GPR84PPARGPPARDPPARA | |
| Tetrabuthylammonium SCHEMBL1716194 | 0.91 | GPR84 (0.77) | AKR1B1GPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515998-B | Synthesis of polyurethanes by chain growth copolymerization | 伊夫·雅努 | 2025-06-24 | — | — | CN | claimed |
| WO-2025118889-A1 | SI-O-SI FRAMEWORK BRIDGED MULTI-NUCLEAR BORON CATALYST, PREPARATION METHOD THEREFOR AND USE THEREOF | 青岛科技大学 | 2025-06-12 | — | — | WO | claimed |
| CN-119875089-A | Polyester-carbon dioxide-based polycarbonate-polyester triblock biodegradable elastomer and preparation method thereof | 中山大学 | 2025-04-25 | — | — | CN | claimed |
| CN-119505214-A | Main chain sulfur-containing polycarbonate copolymer solid electrolyte and preparation method thereof | 郑州大学 | 2025-02-25 | — | — | CN | claimed |
| CN-119350626-A | Si-O-Si based bone bridging polynuclear boron catalyst and preparation method and application thereof | 青岛科技大学 | 2025-01-24 | — | — | CN | claimed |
| CN-119192210-A | Preparation method and application of chiral spiro diborane organic catalyst | 青岛科技大学 | 2024-12-27 | — | — | CN | claimed |
| CN-118206730-A | Tetrachlorophthalic anhydride/ethylene oxide/propylene oxide/carbon dioxide tetrapolymer and preparation method thereof | 中山大学 | 2024-06-18 | — | — | CN | claimed |
| CN-118206728-A | Phthalic anhydride/tetrachlorophthalic anhydride/epoxide/carbon dioxide tetrapolymer and preparation method thereof | 中山大学 | 2024-06-18 | — | — | CN | claimed |
| CN-111117594-B | Electrochromic material and electrochromic device based on dynamic metal-ligand complexation | 吉林大学 | 2024-03-26 | — | — | CN | claimed |
| WO-2023194883-A1 | COPOLYMERIZATION OF ORTHO-PHTHALDEHYDE WITH MONOMERS | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2023-10-12 | — | — | WO | claimed |
| US-20230242699-A1 | POLYCARBAMATE SYNTHESIS VIA CHAIN-GROWTH COPOLYMERIZATION | FENG, Xiaoshuang (CN) | 2023-08-03 | — | — | US | claimed |
| EP-4146716-A1 | POLYCARBAMATE SYNTHESIS VIA CHAIN-GROWTH COPOLYMERIZATION | King Abdullah University Of Science And Technology (SA) | 2023-03-15 | — | — | EP | claimed |
| CN-115109241-A | Ethylene oxide based copolymers | 阿卜杜拉国王科技大学 | 2022-09-27 | — | — | CN | claimed |
| WO-2021224866-A1 | POLYCARBAMATE SYNTHESIS VIA CHAIN-GROWTH COPOLYMERIZATION | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2021-11-11 | — | — | WO | claimed |
| US-20210309801-A1 | ETHYLENE OXIDE-BASED COPOLYMERS | KING ABDULLAH UNIVERSITY OF SCIENCE & TECHNOLOGY (SA) | 2021-10-07 | — | — | US | claimed |
| US-10246558-B2 | Compositions comprising siloxane compounds and methods for using the same | MILLIKEN & COMPANY (US) | 2019-04-02 | — | — | US | claimed |
| EP-3458498-A1 | COMPOSITIONS COMPRISING SILOXANE COMPOUNDS AND METHODS FOR USING THE SAME | Milliken & Company (US) | 2019-03-27 | — | — | EP | claimed |
| CN-109476843-A | Composition comprising silicone compounds and the method using the composition | 美利肯公司 | 2019-03-15 | — | — | CN | claimed |
| US-20170335065-A1 | COMPOSITIONS COMPRISING SILOXANE COMPOUNDS AND METHODS FOR USING THE SAME | MILLIKEN & COMPANY | 2017-11-23 | — | — | US | claimed |
| WO-2017201035-A1 | COMPOSITIONS COMPRISING SILOXANE COMPOUNDS AND METHODS FOR USING THE SAME | MILLIKEN & COMPANY (US) | 2017-11-23 | — | — | WO | claimed |