Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | NT5E | P21589 | 3/20 | 0.54 |
| ▸ | CASP6 | P55212 | 3/20 | 0.46 |
| ▸ | NSD2 | O96028 | 2/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158470 | 0.97 | ALDH1A1 (0.60) | ALDH1A1HSD17B10TSHRTDP1NT5E | |
| SCHEMBL28888353 | 0.95 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TSHRTDP1NT5E | |
| Ammonia Solution, Strong SCHEMBL11246690 | 0.95 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TSHRTDP1NT5E | |
| SCHEMBL668974 | 0.92 | ALDH1A1 (0.60) | ALDH1A1HSD17B10TSHRTDP1NT5E | |
| SCHEMBL29551299 | 0.92 | ALDH1A1 (0.60) | ALDH1A1HSD17B10TSHRTDP1NT5E | |
| SCHEMBL5013229 | 0.86 | LCK (0.55) | ALDH1A1HSD17B10TSHRTDP1NT5E | |
| SCHEMBL124133 | 0.86 | LCK (0.55) | ALDH1A1HSD17B10TSHRTDP1NT5E | |
| SCHEMBL9284620 | 0.85 | ALDH1A1 (0.54) | ALDH1A1HSD17B10TSHRTDP1NT5E | |
| SCHEMBL8871122 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TSHRTDP1NT5E | |
| SCHEMBL219222 | 0.83 | LCK (0.57) | ALDH1A1HSD17B10TSHRTDP1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4608205-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1986-08-26 | — | — | US | disclosed |
| US-4159384-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4123455-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1978-10-31 | — | — | US | disclosed |