Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.58 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PEPD | P12955 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10893585 | 1.00 | ACE (0.58) | ACEACE2L3MBTL1KMT2AELANE | |
| SCHEMBL18018530 | 0.86 | KMT2A (0.53) | ACEACE2L3MBTL1KMT2AREN | |
| SCHEMBL10719498 | 0.85 | KMT2A (0.49) | ACEACE2L3MBTL1KMT2AREN | |
| SCHEMBL10719504 | 0.85 | KMT2A (0.49) | ACEACE2L3MBTL1KMT2AREN | |
| SCHEMBL15373369 | 0.83 | POLB (0.44) | ACEACE2ELANE | |
| SCHEMBL15821242 | 0.82 | ACE (0.49) | ACEACE2RENKDM4EF2 | |
| SCHEMBL10404192 | 0.82 | CMA1 (0.53) | ACEACE2L3MBTL1KMT2AELANE | |
| SCHEMBL10404191 | 0.82 | CMA1 (0.53) | ACEACE2L3MBTL1KMT2AELANE | |
| SCHEMBL5280818 | 0.82 | CMA1 (0.53) | ACEACE2L3MBTL1KMT2AELANE | |
| SCHEMBL8331221 | 0.81 | ACE (0.60) | ACEACE2L3MBTL1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0190852-A2 | Dipeptide derivatives and antihypertensive drugs containing them | AJINOMOTO CO., INC. (JP) | 1986-08-13 | — | — | EP | disclosed |