Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.54 |
| ▸ | KAT2B | Q92831 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8509227 | 0.96 | HCAR3 (0.69) | HCAR3MAPTPKMPOLBPRSS1 | |
| SCHEMBL10888166 | 0.90 | HCAR3 (0.68) | HCAR3MAPTPKMPOLBPRSS1 | |
| SCHEMBL111519 | 0.85 | PRSS1 (0.55) | HCAR3MAPTPKMPOLBPRSS1 | |
| SCHEMBL4980984 | 0.84 | HCAR3 (0.58) | HCAR3MAPTPKMPOLBKAT2B | |
| SCHEMBL29306545 | 0.84 | HCAR3 (0.67) | HCAR3MAPTPKMPOLBPRSS1 | |
| SCHEMBL14906561 | 0.84 | KAT2B (0.74) | HCAR3MAPTPKMPOLBPRSS1 | |
| SCHEMBL10891363 | 0.83 | HCAR3 (0.66) | HCAR3MAPTPKMPOLBKAT2B | |
| SCHEMBL1170111 | 0.83 | HCAR3 (0.66) | HCAR3MAPTPKMPOLBPRSS1 | |
| SCHEMBL20968369 | 0.83 | HCAR3 (0.66) | HCAR3MAPTPKMPOLBPRSS1 | |
| SCHEMBL10428098 | 0.83 | HCAR3 (0.66) | HCAR3MAPTPKMPOLBPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4575378-A | Substituted 4-amino-3-nitrophenols, processes for their preparation and hair-coloring agents containing these compounds | HANS SCHWARZKOPF GMBH (DE) | 1986-03-11 | — | — | US | disclosed |