Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | GJB2 | P29033 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | FGF1 | P05230 | 3/20 | 0.37 |
| ▸ | FGF2 | P09038 | 3/20 | 0.37 |
| ▸ | VEGFA | P15692 | 3/20 | 0.37 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5986141 | 1.00 | BCHE (0.43) | BCHEGJB2MAPK1SSTR1SSTR2 | |
| SCHEMBL9802903 | 1.00 | BCHE (0.43) | BCHEGJB2MAPK1SSTR1SSTR2 | |
| SCHEMBL3344752 | 1.00 | BCHE (0.43) | BCHEGJB2MAPK1SSTR1SSTR2 | |
| SCHEMBL3344756 | 1.00 | BCHE (0.43) | BCHEGJB2MAPK1SSTR1SSTR2 | |
| SCHEMBL15837031 | 0.95 | GJB2 (0.42) | BCHEGJB2MAPK1SSTR1SSTR2 | |
| SCHEMBL16404499 | 0.95 | GJB2 (0.42) | BCHEGJB2MAPK1SSTR1SSTR2 | |
| SCHEMBL12942195 | 0.91 | BCHE (0.45) | BCHEGJB2MAPK1SSTR1SSTR2 | |
| SCHEMBL7041125 | 0.88 | BCHE (0.46) | BCHEGJB2MAPK1CES2CA2 | |
| SCHEMBL7041122 | 0.88 | BCHE (0.46) | BCHEGJB2MAPK1CES2CA2 | |
| SCHEMBL15369122 | 0.87 | GJB2 (0.41) | BCHEGJB2MAPK1SSTR1SSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4614719-A | REACTION OF 1,2,4-TRIAZOLE-CARBOXAMIDE AND RIBOSE DONOR IN PRESENCE OF BREVEBACTERIUM CATALYST | YAMASA SHOYU KABUSHIKI KAISHA (JP) | 1986-09-30 | — | — | US | disclosed |