Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10899503 | 1.00 | ALDH1A1 (0.48) | ALDH1A1APAF1MAPTKDM4EMEN1 | |
| SCHEMBL10899020 | 1.00 | ALDH1A1 (0.48) | ALDH1A1APAF1MAPTKDM4EMEN1 | |
| SCHEMBL10877662 | 0.99 | ALDH1A1 (0.49) | ALDH1A1APAF1MAPTKDM4EMEN1 | |
| SCHEMBL10895957 | 0.94 | ALDH1A1 (0.54) | ALDH1A1APAF1MAPTKDM4EMEN1 | |
| SCHEMBL10894911 | 0.88 | BLM (0.50) | ALDH1A1APAF1MAPTKDM4EMEN1 | |
| SCHEMBL10895797 | 0.80 | BLM (0.50) | ALDH1A1MAPTKDM4EMEN1NPC1 | |
| SCHEMBL10896314 | 0.78 | MALT1 (0.55) | ALDH1A1MAPTKDM4EMEN1NPC1 | |
| SCHEMBL10882592 | 0.78 | S1PR2 (0.45) | THRB | |
| SCHEMBL358215 | 0.78 | SOAT1 (0.57) | ALDH1A1APAF1MAPK1ALOX5 | |
| SCHEMBL369253 | 0.78 | SOAT1 (0.57) | ALDH1A1APAF1MAPK1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4605419-A | STRONG COLORATION ON OXIDATION | SHISEIDO COMPANY LTD. (JP) | 1986-08-12 | — | — | US | disclosed |