Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.31 |
| ▸ | MAOB | P27338 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15066690 | 0.80 | MAPK1 (0.41) | NPC1RAB9AMAPK1SMN1; SMN2LMNA | |
| SCHEMBL55370 | 0.78 | NPC1 (0.40) | NPC1RAB9AMAPK1SMN1; SMN2LMNA | |
| SCHEMBL6542188 | 0.77 | NPC1 (0.39) | NPC1RAB9AMAPK1SMN1; SMN2LMNA | |
| SCHEMBL3278018 | 0.77 | NPC1 (0.39) | NPC1RAB9AMAPK1SMN1; SMN2LMNA | |
| SCHEMBL4468701 | 0.72 | ALDH1A1 (0.34) | MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL3791113 | 0.71 | PDE2A (0.39) | MAPK1SMN1; SMN2LMNAATMMAPT | |
| SCHEMBL578291 | 0.70 | NPC1 (0.44) | NPC1RAB9AMAPK1SMN1; SMN2LMNA | |
| SCHEMBL5053443 | 0.69 | NPC1 (0.32) | NPC1RAB9AMAPK1SMN1; SMN2LMNA | |
| SCHEMBL5110676 | 0.69 | HPGD (0.39) | NPC1RAB9ASMN1; SMN2LMNACASP3 | |
| SCHEMBL27480853 | 0.69 | NPC1 (0.42) | NPC1RAB9AMAPK1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4625027-A | Bisquinazolines useful in color former systems | CIBA-GEIGY CORPORATION (US) | 1986-11-25 | — | — | US | disclosed |