Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD81 | P60033 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22346 | 1.00 | CD81 (0.33) | CD81PTGS1AKR1C3 | |
| Chloromethane SCHEMBL5155285 | 0.95 | CD81 (0.31) | CD81PTGS1AKR1C3 | |
| SCHEMBL14490234 | 0.81 | CYP1A2 (0.31) | — | |
| SCHEMBL17350523 | 0.79 | CD81 (0.30) | CD81 | |
| SCHEMBL28968539 | 0.79 | — | — | |
| SCHEMBL23530327 | 0.78 | TDP1 (0.32) | — | |
| SCHEMBL2064601 | 0.78 | TDP1 (0.32) | — | |
| SCHEMBL26608136 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL19360135 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL28968548 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2788000-B1 | PYRROLOPYRIMIDINES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2018-05-30 | — | — | EP | disclosed |
| EP-2788000-B1 | PYRROLOPYRIMIDINES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2018-05-30 | — | — | EP | disclosed |
| US-8993756-B2 | Pyrrolopyrimidines as janus kinase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2015-03-31 | — | — | US | disclosed |
| US-8993756-B2 | Pyrrolopyrimidines as janus kinase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2015-03-31 | — | — | US | disclosed |
| US-20140349998-A1 | PYRROLOPYRIMIDINES AS JANUS KINASE INHIITORS | MERCK SHARP & DOHME CORP. (US) | 2014-11-27 | — | — | US | disclosed |
| US-20140349998-A1 | PYRROLOPYRIMIDINES AS JANUS KINASE INHIITORS | MERCK SHARP & DOHME CORP. (US) | 2014-11-27 | — | — | US | disclosed |
| EP-2788000-A1 | PYRROLOPYRIMIDINES AS JANUS KINASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2014-10-15 | — | — | EP | disclosed |
| WO-2013085802-A1 | PYRROLOPYRIMIDINES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2013-06-13 | — | — | WO | disclosed |
| WO-2013085802-A1 | PYRROLOPYRIMIDINES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2013-06-13 | — | — | WO | disclosed |
| US-4604347-A | Analytical element for dry analysis | FUJI PHOTO FILM CO., LTD. (JP) | 1986-08-05 | — | — | US | disclosed |
| EP-0116361-A2 | Analytical element for dry analysis | FUJI PHOTO FILM CO., LTD. (JP) | 1984-08-22 | — | — | EP | disclosed |
| US-4042476-A | TITANIUM DIOXIDE-ACRYLIC POLYMER EMULSION | CELANESE CORPORATION (US) | 1977-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140349998-A1 | PYRROLOPYRIMIDINES AS JANUS KINASE INHIITORS | JAK3, JAK1, JAK2 | CD81 4160/4885PTGS1 211/4885AKR1C3 1096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.